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Title:
LYMPHOCYTIC MEMBRANE PROTEINS
Document Type and Number:
WIPO Patent Application WO2000037639
Kind Code:
A3
Abstract:
The invention provides human lymphocytic membrane proteins (LMPRO) and polynucleotides which identify and encode LMPRO. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of LMPRO.

Inventors:
TANG Y TOM (US)
YUE HENRY (US)
BAUGHN MARIAH R (US)
Application Number:
PCT/US1999/029691
Publication Date:
November 16, 2000
Filing Date:
December 13, 1999
Export Citation:
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Assignee:
INCYTE PHARMA INC (US)
TANG Y TOM (US)
YUE HENRY (US)
BAUGHN MARIAH R (US)
International Classes:
C12N15/09; A61K38/00; A61K45/00; A61P1/00; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P7/04; A61P7/06; A61P7/08; A61P9/10; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/06; A61P19/10; A61P21/02; A61P21/04; A61P25/00; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P35/00; A61P35/02; A61P37/08; C07K14/47; C07K14/705; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12P21/02; C12Q1/68; (IPC1-7): C12N15/12; A61K38/17; C07K14/705; C07K16/18; C07K16/28; C12Q1/68
Domestic Patent References:
WO1993016178A21993-08-19
WO1991010682A11991-07-25
WO1999007891A11999-02-18
Foreign References:
EP0386906A11990-09-12
Other References:
DATABASE EMEST2 EMBL; 12 December 1997 (1997-12-12), STRAUSBERG R: "nv15c11.s1 NCI_CGAP_Pr22 Homo sapiens cDNA clone IMAGE:1220276 similar to TR:Q12912 Q12912 LYMPHOID-RESTRICTED MEMBRANE PROTEIN", XP002140095
BEHRENS T W ET AL.: "Jaw1, a lymphoid-restricted membrane protein localized to the endoplasmatic reticulum", JOURNAL OF IMMUNOLOGY, vol. 153, no. 2, 15 July 1994 (1994-07-15), pages 682 - 690, XP002140092
MOSTERT M C ET AL.: "Identification of the critical region of 12p over-representation in testicular germ cell tumors of adolescents and adults", ONCOGENE, vol. 16, no. 20, May 1998 (1998-05-01), pages 2617 - 2627, XP000914740
SHAUGHNESSY J D JR ET AL.: "Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1", ONCOGENE, vol. 18, no. 12, 25 March 1999 (1999-03-25), pages 2069 - 2084, XP000914720
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