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Title:
MEDICINES COMPRISING Rho KINASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/1998/006433
Kind Code:
A1
Abstract:
Novel medicines comprising Rho kinase inhibitors, such as hypertension remedy, angina remedy, cerebrovascular twitching inhibitor, asthma remedy, premature birth preventive, arteriosclerosis remedy, anticancer drug, anti-phlogistic, immunosuppressive, autoimmune disease remedy, anti-AIDS drug, contraceptive, digestive infection preventive, osteoporosis remedy, retinopathy remedy, and cerebral function ameliorant; and reagents and diagnostic agents comprising Rho kinase inhibitors.

Inventors:
UEHATA MASAYOSHI (JP)
ONO TAKASHI (JP)
SATOH HIROYUKI (JP)
YAMAGAMI KEIJI (JP)
KAWAHARA TOSHIO (JP)
Application Number:
PCT/JP1997/002793
Publication Date:
February 19, 1998
Filing Date:
August 08, 1997
Export Citation:
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Assignee:
YOSHITOMI PHARMACEUTICAL (JP)
UEHATA MASAYOSHI (JP)
ONO TAKASHI (JP)
SATOH HIROYUKI (JP)
YAMAGAMI KEIJI (JP)
KAWAHARA TOSHIO (JP)
International Classes:
A61K31/00; A61K31/437; A61K31/4409; A61K31/4545; A61K31/496; A61K31/551; A61K45/00; G01N33/48; A61K31/16; (IPC1-7): A61K45/00; A61K31/16; A61K31/165; A61K31/195; A61K49/00; A61K31/445; A61K31/50; A61K31/495; A61K31/44; C07D213/81; C07D401/12; C07D409/14; C07D401/14; C07D405/14; C07D211/78
Domestic Patent References:
WO1995028387A11995-10-26
Foreign References:
JPS6289679A1987-04-24
JPH03218356A1991-09-25
JPH04273821A1992-09-30
JPH05194401A1993-08-03
JPH0641080A1994-02-15
JPS57200366A1982-12-08
JPS61227581A1986-10-09
JPH02256617A1990-10-17
JPH04264030A1992-09-18
JPH0656668A1994-03-01
JPH0680569A1994-03-22
JPH06293643A1994-10-21
JPH0741424A1995-02-10
JPH07277979A1995-10-24
JPS57200366A1982-12-08
JPS58121278A1983-07-19
JPS58121279A1983-07-19
JPS5993054A1984-05-29
JPS6081168A1985-05-09
JPS61152658A1986-07-11
JPS61227581A1986-10-09
JPS62103066A1987-05-13
US4678783A1987-07-07
Other References:
See also references of EP 0956865A4
Attorney, Agent or Firm:
Takashima, Hajime (3-9 Hiranomachi 3-chome, Chuo-k, Osaka-shi Osaka 541, JP)
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