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Title:
MACROCYCLIC TLR7 AGONIST, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/156678
Kind Code:
A1
Abstract:
A macrocyclic TLR7 agonist, and a preparation method therefor, a pharmaceutical composition thereof and the use thereof. The macrocyclic TLR7 agonist is a compound as represented by formula I. The compound is new in terms of structure, has relatively good activity and has good application prospects.

Inventors:
TANG GUOZHI (CN)
HUANG MENGWEI (CN)
MA DAWEI (CN)
Application Number:
PCT/CN2022/072556
Publication Date:
July 28, 2022
Filing Date:
January 18, 2022
Export Citation:
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Assignee:
SHANGHAI VISONPHARMA CO LTD (CN)
International Classes:
C07D487/04; A61K31/519; A61K31/5377; A61P1/16; A61P31/12; A61P31/14; A61P31/18; A61P31/20
Domestic Patent References:
WO2017188287A12017-11-02
WO2020074006A12020-04-16
WO2020160711A12020-08-13
WO2020188448A12020-09-24
Foreign References:
CN110372703A2019-10-25
CN105367576A2016-03-02
CN112105620A2020-12-18
Attorney, Agent or Firm:
SHANGHAI BESINGIP INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
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