Title:
MARKER FOR PANCREATIC CANCER AND INTRADUCTAL PAPILLARY MUCINOUS TUMORS
Document Type and Number:
WIPO Patent Application WO/2017/098915
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a marker that indicates pancreatic cancer and intraductal papillary mucinous tumors, with high sensitivity and specificity. Furthermore, the purpose of the present invention is also to provide a diagnostic kit for pancreatic cancer and intraductal papillary mucinous tumors, which detects this marker, and a method for evaluating metastatic pancreatic cancer and intraductal papillary mucinous tumors, using the marker. This marker of pancreatic cancer and intraductal papillary mucinous tumors is characterized by including one or more proteins, selected from the group consisting of secretoglobin family-1D member 2, and podocalyxin-like protein. Furthermore, this diagnostic kit for pancreatic cancer and intraductal papillary mucinous tumors is characterized by including an antibody for one or more proteins selected from the group consisting of secretoglobin family-1D member 2, and podocalyxin-like protein.
Inventors:
TANIUCHI KEISUKE (JP)
Application Number:
PCT/JP2016/084537
Publication Date:
June 15, 2017
Filing Date:
November 22, 2016
Export Citation:
Assignee:
NAT UNIV CORP KOCHI UNIV (JP)
International Classes:
C07K14/47; C12N15/09; G01N33/53; G01N33/68
Foreign References:
| US7282207B1 | 2007-10-16 | |||
| US20060294607A1 | 2006-12-28 | |||
| JP2015212302A | 2015-11-26 | |||
| JP2013027387A | 2013-02-07 |
Other References:
TERESA J. ET AL.: "Podocalyxin-like protein 1 expression is useful to differentiate pancreatic ductal adenocarcinomas from adenocarcinomas of the biliary and gastrointestinal tracts", HUM. PATHOL., vol. 38, 2007, pages 359 - 364, XP005734366, DOI: 10.1016/j.humpath.2006.08.025
KEISUKE TANIUCHI: "Kesseichu no Suigan Saibo Exosome Yurai mRNA o Mochiita Suigan Shinki Shindanho no Kakuritsu ni Mukete", THE JOURNAL OF JAPAN PANCREAS SOCIETY, vol. 30, no. 3, 18 May 2015 (2015-05-18), pages 262, XP009515239
ONCOTARGET, vol. 5, 2014, pages 6832 - 6845
See also references of EP 3388448A4
KEISUKE TANIUCHI: "Kesseichu no Suigan Saibo Exosome Yurai mRNA o Mochiita Suigan Shinki Shindanho no Kakuritsu ni Mukete", THE JOURNAL OF JAPAN PANCREAS SOCIETY, vol. 30, no. 3, 18 May 2015 (2015-05-18), pages 262, XP009515239
ONCOTARGET, vol. 5, 2014, pages 6832 - 6845
See also references of EP 3388448A4
Attorney, Agent or Firm:
UEKI, Kyuichi et al. (JP)
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