MEROSIN, NUCLEIC ACIDS ENCODING, FRAGMENTS AND USES THEREOF

Title:

MEROSIN, NUCLEIC ACIDS ENCODING, FRAGMENTS AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO1991011462

Kind Code:

A3

Abstract:

A substantially pure heterotrimeric laminin variant comprising the structure M-X-B2, wherein M is the M polypeptide of merosin; X is selected from the group consisting of the B1 chain of laminin and S-laminin; and B2 is the B2 chain of laminin.

Inventors:

ENGVALL EVA (US)
LEIVO ILMO (US)
SANES JOSHUA R (US)

Application Number:

PCT/US1991/000631

Publication Date:

October 03, 1991

Filing Date:

January 30, 1991

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Assignee:

JOLLA CANCER RES FOUND (US)
UNIV WASHINGTON (US)

International Classes:

A61K39/395; A61P25/00; A61P43/00; C07K14/00; C07K14/78; C07K16/00; C07K16/18; C07K19/00; C12N1/21; C12N15/02; C12N15/09; C12N15/12; A61K38/00; C12P21/00; C12P21/08; C12Q1/68; G01N33/53; G01N33/68; C12R1/91; (IPC1-7): C07K13/00; C12N15/12; A61K37/02; A61K39/395; C07K3/18; C12N1/21; C12P21/02; C12P21/08; C12Q1/68; G01N33/68

Other References:

XP002084296
DATABASE CAPLUS [online] 20 June 1983 (1983-06-20), "ISOLATION OF LAMININ FROM HUMAN PLACENTAL BASEMENT MEMBRANES: AMNION, CHORION AND CHORIONIC MICROVESSELS", XP002084299, accession no. STN Database accession no. 1983:213310
XP002084297
XP002084298
DATABASE CAPLUS [online] 4 March 1991 (1991-03-04), "DISTRIBUTION AND ISOLATION OF FOUR LAMININ VARIANTS:TISSUES RESTRICTED DISTRIBUTION OF HETREOTRIMERS ASSEMBLED FROM FIVE DIFFERENT SUBUNITS", XP002084300, accession no. STN Database accession no. 1991:79032

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