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Title:
METHOD AND APPARATUS FOR MULTIMODAL IMAGING OF BIOLOGICAL TISSUE
Document Type and Number:
WIPO Patent Application WO/2010/120769
Kind Code:
A3
Abstract:
The present invention is directed to a novel multi- wavelength imaging method and apparatus that enables rapid imaging of tissue regions with accurate identification of tissue types within the region. Optical properties, such as co- polarized or cross-polarized fluorescence or reflectance intensity, optical density and/or reflectance, can be determined at a plurality of locations within the tissue region for each wavelength. Said properties at the two wavelengths, including calculated derivatives of the optical property with respect to wavelength, can be analyzed to image tissue structures and identify tissue types within the tissue region more accurately than can be achieved based on properties measured at a single wavelength.

Inventors:
YAROSLAVSKY ANNA N (US)
SALOMATINA ELENA (US)
ANDERSON RICHARD ROX (US)
Application Number:
PCT/US2010/030880
Publication Date:
January 20, 2011
Filing Date:
April 13, 2010
Export Citation:
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Assignee:
GEN HOSPITAL CORP (US)
YAROSLAVSKY ANNA N (US)
SALOMATINA ELENA (US)
ANDERSON RICHARD ROX (US)
International Classes:
G01N21/25; G01N21/64; G01N33/483
Foreign References:
US6280386B12001-08-28
US20080024860A12008-01-31
Other References:
MUNIR Y. AL-ARASHI ET AL.: "Multimodal Confocal Microscopy For Diagnosing No n melanoma Skin Cancers", LASERS IN SURGERY AND MEDICINE, vol. 39, 2007, pages 696 - 705, XP055003025
Attorney, Agent or Firm:
LAURO, Peter C. et al. (P.O. Box 55874Boston, MA, US)
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