Title:
METHOD AND APPARATUS FOR PROVIDING OPTIMAL IMAGES OF A MICROSCOPE SPECIMEN
Document Type and Number:
WIPO Patent Application WO2006021767
Kind Code:
A3
Abstract:
A method for providing image data for an optimal image of a microscope field of view of a specimen is described. The method uses a microscopy digital imaging apparatus to capture a plurality of digital images of a specimen contained within a microscope field of view at a corresponding plurality of microscope focusing positions. The plurality of digital images is processed to obtain data representing a single optimal image of the microscope field of view, which is stored in memory. The optimal image combines or utilizes the image information from the plurality of images, and is particularly useful for specimens that have a depth of view or thickness.
Inventors:
MADDISON JOHN R (GB)
Application Number:
PCT/GB2005/003267
Publication Date:
April 20, 2006
Filing Date:
August 22, 2005
Export Citation:
Assignee:
MEDICAL SOLUTIONS (GB)
MADDISON JOHN R (GB)
MADDISON JOHN R (GB)
International Classes:
G02B21/36; G06T5/50
Domestic Patent References:
| WO2003023482A1 | 2003-03-20 |
Foreign References:
| US6320979B1 | 2001-11-20 | |||
| US4661986A | 1987-04-28 | |||
| US6201899B1 | 2001-03-13 | |||
| US6433325B1 | 2002-08-13 | |||
| EP1336888A1 | 2003-08-20 | |||
| EP0994433A1 | 2000-04-19 |
Other References:
KODAMA K ET AL: "ACQUISITION OF AN ALL-FOCUSED IMAGE BY THE USE OF MULTIPLE DIFFERENTLY FOCUSED IMAGES", SYSTEMS & COMPUTERS IN JAPAN, WILEY, HOBOKEN, NJ, US, vol. 29, no. 1, January 1998 (1998-01-01), pages 1 - 11, XP000742966, ISSN: 0882-1666
KODAMA K ET AL: "GENERATION OF ARBITRARILY FOCUSED IMAGES BY USING MULTIPLE DIFFERENTLY FOCUSED IMAGES", JOURNAL OF ELECTRONIC IMAGING, SPIE / IS & T, US, vol. 7, no. 1, January 1998 (1998-01-01), pages 138 - 144, XP000732634, ISSN: 1017-9909
VITRIA J ET AL: "Reconstructing 3D light microscopic images using the EM algorithm", PATTERN RECOGNITION LETTERS, NORTH-HOLLAND PUBL. AMSTERDAM, NL, vol. 17, no. 14, 30 December 1996 (1996-12-30), pages 1491 - 1498, XP004017164, ISSN: 0167-8655
KODAMA K ET AL: "GENERATION OF ARBITRARILY FOCUSED IMAGES BY USING MULTIPLE DIFFERENTLY FOCUSED IMAGES", JOURNAL OF ELECTRONIC IMAGING, SPIE / IS & T, US, vol. 7, no. 1, January 1998 (1998-01-01), pages 138 - 144, XP000732634, ISSN: 1017-9909
VITRIA J ET AL: "Reconstructing 3D light microscopic images using the EM algorithm", PATTERN RECOGNITION LETTERS, NORTH-HOLLAND PUBL. AMSTERDAM, NL, vol. 17, no. 14, 30 December 1996 (1996-12-30), pages 1491 - 1498, XP004017164, ISSN: 0167-8655
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