Title:
METHOD FOR DETECTING THE METHYLATION OF COLON-CANCER-SPECIFIC METHYLATION MARKER GENES FOR COLON CANCER DIAGNOSIS
Document Type and Number:
WIPO Patent Application WO/2011/055916
Kind Code:
A3
Abstract:
The present invention relates to a method for detecting the methylation of colon-cancer-specific methylation marker genes for colon cancer diagnosis, and more particularly, to a method which involves detecting the methylation of colon-cancer-specific methylation marker genes which are specifically methylated in colon cancer cells, and providing information for colon cancer diagnosis. Using the methylation detection method, and a composition, a kit and a nucleic acid chip for diagnosis according to the present invention, colon cancer can be diagnosed in an early transformation stage to enable the early diagnosis of colon cancer. The method of the present invention enables the diagnosis of colon cancer to be performed in a more accurate and quick manner as compared to conventional methods, and therefore can be effectively used.
Inventors:
AN SUNG WHAN (KR)
MOON YOUNG HO (KR)
OH TAE JEONG (KR)
CHUNG HYUN CHEOL (KR)
MOON YOUNG HO (KR)
OH TAE JEONG (KR)
CHUNG HYUN CHEOL (KR)
Application Number:
PCT/KR2010/007030
Publication Date:
August 04, 2011
Filing Date:
October 14, 2010
Export Citation:
Assignee:
GENOMICTREE INC (KR)
AN SUNG WHAN (KR)
MOON YOUNG HO (KR)
OH TAE JEONG (KR)
CHUNG HYUN CHEOL (KR)
AN SUNG WHAN (KR)
MOON YOUNG HO (KR)
OH TAE JEONG (KR)
CHUNG HYUN CHEOL (KR)
International Classes:
C12Q1/68; C12N15/11
Foreign References:
| DE20121960U1 | 2004-01-15 | |||
| US20090208514A1 | 2009-08-20 | |||
| US20080292546A1 | 2008-11-27 | |||
| US20100131432A1 | 2010-05-27 |
Other References:
SHYR-YI LIN AN ET AL.: "Promoter CpG Methylation of Caveolin-1 in Sporadic Colorectal Cancer", ANTICANCER RESEARCH, vol. 24, 2004, pages 1645 - 1650, XP008155805
Attorney, Agent or Firm:
LEE, Cheo Young (Yeosam Bldg. 648-23,Yeoksam-dong, Gangnam-gu, Seoul 135-080, KR)
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Claims: