METHOD OF EXAMINING CANCER BY ASSAYING AUTOANTIBODY AGAINST MDM2 AND REAGENT THEREFOR

Title:

METHOD OF EXAMINING CANCER BY ASSAYING AUTOANTIBODY AGAINST MDM2 AND REAGENT THEREFOR

Document Type and Number:

WIPO Patent Application WO/2001/075449

Kind Code:

A1

Abstract:

A novel method of examining cancer by assaying an autoantibody against MDM2 in the blood and a reagent and a kit therefor. For example, cancer is examined by an immunological method with the use of a peptide fragment of MDM2 as an antigen and anti-MDM2 antibody, which is optionally labeled, obtained from this antigen as an antibody for assaying the autoantibody as described above.

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Inventors:

SEINO YUKO (JP)

Application Number:

PCT/JP2001/002723

Publication Date:

October 11, 2001

Filing Date:

March 30, 2001

Export Citation:

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Assignee:

NIPPON KAYAKU KK (JP)
SEINO YUKO (JP)

International Classes:

C07K14/47; G01N33/574; (IPC1-7): G01N33/574; C07K7/08; G01N33/53

Domestic Patent References:

WO1995014233A2

1995-05-26

Foreign References:

DE4339533A1

1995-06-14

Other References:

CANCER LETTERS, vol. 96, 1995, pages 111 - 115, XP002941458
NATURE, vol. 358, 1992, pages 80 - 83, XP002941459
See also references of EP 1271152A4

Attorney, Agent or Firm:

Saeki, Norio (Taka-ai Building 15-2 Nihonbashi 3-chome Chuo-ku, Tokyo, JP)

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