Title:
METHOD FOR PRODUCING CHROMANE DERIVATIVES THAT ARE DEVOID OF ENANTIOMERS AND ARE SUBSTITUTED IN POSITION 2
Document Type and Number:
WIPO Patent Application WO2005037817
Kind Code:
A3
Abstract:
The invention relates to a method for producing chromane derivatives that are devoid of enantiomers and are substituted in position 2, from corresponding chromane-2-carboxylic acid esters.
Inventors:
DEVANT RALF DI
BOKEL HEINZ-HERMANN (DE)
REUBOLD HELMUT (DE)
PFLUG HERBERT (DE)
KNIERIEME RALF (DE)
BOKEL HEINZ-HERMANN (DE)
REUBOLD HELMUT (DE)
PFLUG HERBERT (DE)
KNIERIEME RALF (DE)
Application Number:
PCT/EP2004/010399
Publication Date:
June 23, 2005
Filing Date:
September 16, 2004
Export Citation:
Assignee:
MERCK PATENT GMBH (DE)
BOKEL HEINZ-HERMANN (DE)
REUBOLD HELMUT (DE)
PFLUG HERBERT (DE)
KNIERIEME RALF (DE)
DEVANT MARIA HF (DE)
BOKEL HEINZ-HERMANN (DE)
REUBOLD HELMUT (DE)
PFLUG HERBERT (DE)
KNIERIEME RALF (DE)
DEVANT MARIA HF (DE)
International Classes:
C07D311/58; C07D311/66; (IPC1-7): C07D311/58; C07D311/66
Other References:
A. STREITWIESER, C.H. HEATHCOCK: "organische chemie", 1980, VERLAG CHEMIE, WEINHEIM, XP002317016
CH. B. CHAPLEO: "alpha-Adrenoreceptor Reagents. 2. Effects of Modification of the 1,4-Benzodioxan Ring System on alpha-Adrenoreceptor Activity", J. MED. CHEM., vol. 27, 1984, pages 570 - 576, XP002317015
CH. B. CHAPLEO: "alpha-Adrenoreceptor Reagents. 2. Effects of Modification of the 1,4-Benzodioxan Ring System on alpha-Adrenoreceptor Activity", J. MED. CHEM., vol. 27, 1984, pages 570 - 576, XP002317015
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