Title:
METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE
Document Type and Number:
WIPO Patent Application WO/2023/149487
Kind Code:
A1
Abstract:
The present invention pertains to a method for producing a pyrrole-imidazole polyamide, the method comprising the following steps A1 and A2. Step A1: A reduction step for reducing compound 1 to obtain compound 2; Step A2: An extension step of reacting compound 3 with compound 2 to obtain compound 4 [Compounds 1-4 are as defined in the specification.]
Inventors:
NEMOTO TETSUHIRO (JP)
NAKAJIMA MASAYA (JP)
KANEDA ATSUSHI (JP)
NAKAJIMA MASAYA (JP)
KANEDA ATSUSHI (JP)
Application Number:
PCT/JP2023/003274
Publication Date:
August 10, 2023
Filing Date:
February 01, 2023
Export Citation:
Assignee:
UNIV CHIBA NAT UNIV CORP (JP)
International Classes:
C07D207/42; C07D233/95; C07D403/12; C07D403/14; C08G69/12
Domestic Patent References:
| WO2003000683A1 | 2003-01-03 |
Foreign References:
| JP2004517830A | 2004-06-17 | |||
| US20070265240A1 | 2007-11-15 | |||
| JP2006509027A | 2006-03-16 | |||
| JPH0692933A | 1994-04-05 | |||
| JPH0827146A | 1996-01-30 |
Other References:
BHATTACHARYA, S. THOMAS, M.: "Facile synthesis of oligopeptide distamycin analogs devoid of hydrogen bond donors or acceptors at the N-terminus: sequence-specific duplex DNA binding as a function of peptide chain length", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM , NL, vol. 41, no. 29, 15 July 2000 (2000-07-15), Amsterdam , NL , pages 5571 - 5575, XP004209515, ISSN: 0040-4039, DOI: 10.1016/S0040-4039(00)00802-9
YOSHIDA JUN-ICHI, SEIJI SUGA, AIICHIRO NAGAKI: "Selective Organic Reactions Using Microreactors", JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY, vol. 63, no. 5, 1 January 2005 (2005-01-01), pages 511 (93) - 522 (104), XP093082928
NAGAKI, AIICHIRO; ASHIKARI YOSUKE: "Special Issue on Microfluidic Engineering and Process Intensification", THE CHEMICAL TIMES, KANTO KAGAKU KABUSHIKI GAISHA, JAPAN, vol. 263, 31 December 2021 (2021-12-31), Japan , pages 3 - 6, XP009548406, ISSN: 0285-2446
YOSHIDA JUN-ICHI, SEIJI SUGA, AIICHIRO NAGAKI: "Selective Organic Reactions Using Microreactors", JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY, vol. 63, no. 5, 1 January 2005 (2005-01-01), pages 511 (93) - 522 (104), XP093082928
NAGAKI, AIICHIRO; ASHIKARI YOSUKE: "Special Issue on Microfluidic Engineering and Process Intensification", THE CHEMICAL TIMES, KANTO KAGAKU KABUSHIKI GAISHA, JAPAN, vol. 263, 31 December 2021 (2021-12-31), Japan , pages 3 - 6, XP009548406, ISSN: 0285-2446
Attorney, Agent or Firm:
OHTANI PATENT OFFICE (JP)
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