METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF

Title:

METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF

Document Type and Number:

WIPO Patent Application WO2004110339

Kind Code:

A3

Abstract:

The invention provides novel methods for selective targeting of chemical compounds to cells undergoing a death process, in particular apoptosis, and to platelets undergoing activation during blood coagulation. The invention further provides compounds to be used in said methods for medical practice, for diagnostic and therapeutic purposes.

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Inventors:

ZIV ILAN (IL)
SHIRVAN ANAT (IL)

Application Number:

PCT/IL2004/000535

Publication Date:

July 27, 2006

Filing Date:

June 17, 2004

Export Citation:

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Assignee:

NST NEUROSURVIVAL TECHNOLOGIES (IL)
ZIV ILAN (IL)
SHIRVAN ANAT (IL)

International Classes:

A61K31/195; A61K31/198; A61K49/00; A61K51/04; C07C229/36; C07C309/00; C07C309/47; C07C311/42; C07C323/57; A61K

Other References:

NIIMI T. ET AL: "Design and Synthesis of Non-peptic Inhibitors For The Syk C-Terminal SH2 Domain Based on Structure-Based In-Silico Screening", J. MED. CHEM., vol. 44, 2001, pages 4737 - 4740, XP002255446

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