Title:
A METHOD TO RAPIDLY PREPARE AND SCREEN FORMULATIONS AND COMPOSITIONS CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO2003095515
Kind Code:
A3
Abstract:
A new method to rapidly produce and screen polymer-, xerogel-, bioceramic- and bioglass-based formulations is described. The approach is based on a high-speed pin printer and imaging with an epi-fluorescence microscope/charge coupled device detector. By using this method one can produce and screen over 600 formulations/hr and rapidly identify lead formulations and/or compositions that are useful for the development of devices such as medical devices and (bio)sensors.
Inventors:
BRIGHT FRANCK V (US)
GARDELLA JOSEPH A (US)
HARD ROBERT (US)
HICKS WESLEY L JR (US)
GARDELLA JOSEPH A (US)
HARD ROBERT (US)
HICKS WESLEY L JR (US)
Application Number:
PCT/US2003/014189
Publication Date:
July 29, 2004
Filing Date:
May 07, 2003
Export Citation:
Assignee:
UNIV NEW YORK STATE RES FOUND (US)
BRIGHT FRANCK V (US)
GARDELLA JOSEPH A (US)
HARD ROBERT (US)
HICKS WESLEY L JR (US)
BRIGHT FRANCK V (US)
GARDELLA JOSEPH A (US)
HARD ROBERT (US)
HICKS WESLEY L JR (US)
International Classes:
G01N21/00; G01N33/543; (IPC1-7): G01N33/53
Other References:
LUNDGREN J.S. ET AL: "Dynamics of Acrylodan-Labeled Bovine and Human Serum Albumin Sequestered within Aerosol-OT Reverse Micelles", ANAL. CHEM., vol. 67, 1995, pages 3775 - 3781, XP002978563
JORDAN J.D. ET AL: "Dynamics of Acrylodan-Labeled Bovine and Human Serum Albumin Entrapped in a Sol-Gel-Derived Biogel", ANAL. CHEM., vol. 67, 1995, pages 2436 - 2443, XP002978564
ARENKOV P. ET AL: "Protein Microchips: Use for Immunoassay and Enzymatic Reactions", ANAL. BIOCHEM., vol. 278, no. 2, February 2000 (2000-02-01), pages 123 - 131, XP002271989
BENOIT MA ET AL: "Antibiotic-loaded plaster of Paris implants coated with poly lactide-co-glycolide as a controlled release delivery system for the treatment of bone infections", INT. ORTHOP., vol. 21, no. 6, 1997, pages 403 - 408, XP002978565
GERRITSEN M. ET AL: "Biocompatibility evaluation of sol-gel coatings for subcutaneously implantable glucose sensors", BIOMATERIALS, vol. 21, no. 1, 2000, pages 71 - 78, XP002978566
JORDAN J.D. ET AL: "Dynamics of Acrylodan-Labeled Bovine and Human Serum Albumin Entrapped in a Sol-Gel-Derived Biogel", ANAL. CHEM., vol. 67, 1995, pages 2436 - 2443, XP002978564
ARENKOV P. ET AL: "Protein Microchips: Use for Immunoassay and Enzymatic Reactions", ANAL. BIOCHEM., vol. 278, no. 2, February 2000 (2000-02-01), pages 123 - 131, XP002271989
BENOIT MA ET AL: "Antibiotic-loaded plaster of Paris implants coated with poly lactide-co-glycolide as a controlled release delivery system for the treatment of bone infections", INT. ORTHOP., vol. 21, no. 6, 1997, pages 403 - 408, XP002978565
GERRITSEN M. ET AL: "Biocompatibility evaluation of sol-gel coatings for subcutaneously implantable glucose sensors", BIOMATERIALS, vol. 21, no. 1, 2000, pages 71 - 78, XP002978566
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