Title:
METHODS AND COMPOSITIONS FOR INHIBITING NEOPLASTIC CELL GROWTH
Document Type and Number:
WIPO Patent Application WO2000073348
Kind Code:
A3
Abstract:
The present invention concerns methods and compositions for inhibiting neoplastic cell growth. In particular, the present invention concerns antitumor compositions and methods for the treatment of tumors. The invention further concerns screening methods for identifying growth inhibitory, e.g., antitumor compounds. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Inventors:
BAKER KEVIN P (US)
GODDARD AUDREY (US)
GURNEY AUSTIN L (US)
HEBERT CAROLINE (US)
HENZEL WILLIAM (US)
KABAKOFF RHONA C (US)
SHELTON DAVID L (US)
SMITH VICTORIA (US)
WATANABE COLIN K (US)
WOOD WILLIAM I (US)
GODDARD AUDREY (US)
GURNEY AUSTIN L (US)
HEBERT CAROLINE (US)
HENZEL WILLIAM (US)
KABAKOFF RHONA C (US)
SHELTON DAVID L (US)
SMITH VICTORIA (US)
WATANABE COLIN K (US)
WOOD WILLIAM I (US)
Application Number:
PCT/US2000/014941
Publication Date:
July 05, 2001
Filing Date:
May 30, 2000
Export Citation:
Assignee:
GENENTECH INC (US)
BAKER KEVIN P (US)
GODDARD AUDREY (US)
GURNEY AUSTIN L (US)
HEBERT CAROLINE (US)
HENZEL WILLIAM (US)
KABAKOFF RHONA C (US)
SHELTON DAVID L (US)
SMITH VICTORIA (US)
WATANABE COLIN K (US)
WOOD WILLIAM I (US)
BAKER KEVIN P (US)
GODDARD AUDREY (US)
GURNEY AUSTIN L (US)
HEBERT CAROLINE (US)
HENZEL WILLIAM (US)
KABAKOFF RHONA C (US)
SHELTON DAVID L (US)
SMITH VICTORIA (US)
WATANABE COLIN K (US)
WOOD WILLIAM I (US)
International Classes:
A61K38/00; A61K39/395; A61K45/00; A61P35/00; A61P35/02; C07K14/435; C07K14/47; C07K16/18; C07K19/00; C12N1/19; C12N1/21; C12N5/07; C12N5/077; C12N5/09; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12P21/08; (IPC1-7): C12N15/12; C07K14/47; A61K38/17; G01N33/53; G01N33/574; C12N15/62; C07K16/18
Domestic Patent References:
| WO1999014327A2 | 1999-03-25 | |||
| WO1997025349A1 | 1997-07-17 | |||
| WO1999018203A2 | 1999-04-15 | |||
| WO1991015510A1 | 1991-10-17 | |||
| WO1995009005A1 | 1995-04-06 | |||
| WO2000015666A2 | 2000-03-23 |
Foreign References:
| EP0315289A2 | 1989-05-10 |
Other References:
See also references of EP 1185648A2
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