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Title:
A METHODS AND INTERFACES FOR SINGLE AND MULTIDIMENTIONAL SEPARATIONS FOR CHARACTERIZATION AND/OR IDENTIFICATION OF MOLECULES BY MASS SPECTROMETRY
Document Type and Number:
WIPO Patent Application WO2006062471
Kind Code:
B1
Abstract:
The present invention relates a use of the electrocapture-based separation technology combined with mass spectrometry (e.g. sequence of polypeptides by collision-induce dissociation mass spectrometry, for the identification and/or characterization molecules of interest). In addition, it relates physical interfaces between electrocapture-based separations and different types mass spectrometers for on-line analysis, as well as the coupling of electrocapture-based separations, liquid chromatography and different types of mass spectrometrometers. It also relates the combination of the electrocapture-base separation technology with other liquid separation methods, as e.g. liquid chromatography, in order to achieve multidimensional separations prior mass spectrometrical analysis. The invention also relates to a separation device comprising a capture device, a fluidic connector e.g. an electrospray source, an electrospray interface -source and a mass spectrometer.

Inventors:
ASTORGA-WELLS JUAN (SE)
Application Number:
PCT/SE2005/001844
Publication Date:
December 28, 2006
Filing Date:
December 06, 2005
Export Citation:
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Assignee:
CAPTURE DEVICE AB (SE)
ASTORGA-WELLS JUAN (SE)
International Classes:
H01J49/04; G01N27/447; G01N30/72; G01N30/46; G01N
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