Title:
METHODS AND MATERIALS RELATING TO STEM CELL GROWTH FACTOR-LIKE POLYPEPTIDES AND POLYNUCLEOTIDES
Document Type and Number:
WIPO Patent Application WO2002051868
Kind Code:
A3
Abstract:
The invention novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human and mouse secreted stem cell growth factor-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries prepared from mouse bone marrow and human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, placental, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
Inventors:
NISHIKAWA MITSUO
LABAT IVAN
DRMANAC RADOJE T
TANG Y TOM
CHAO CHENG-CHI
MIZE NANCY
CHILDS JOHN
LABAT IVAN
DRMANAC RADOJE T
TANG Y TOM
CHAO CHENG-CHI
MIZE NANCY
CHILDS JOHN
Application Number:
PCT/IB2001/002839
Publication Date:
May 30, 2003
Filing Date:
July 25, 2001
Export Citation:
Assignee:
KIRIN BREWERY (JP)
International Classes:
G01N33/50; A61K31/7088; A61K38/00; A61K45/00; A61K48/00; A61P25/28; A61P35/00; C07K14/475; C07K16/22; C12M1/00; C12M1/34; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/02; C12Q1/02; C12Q1/68; G01N33/15; G01N33/53; G01N33/566; G01N37/00; (IPC1-7): C07K14/705; A61K31/713; A61K38/17; A61K39/395; C07K14/475; C07K16/28; C12N5/10; C12Q1/68; G01N33/53; G01N33/566
Domestic Patent References:
| WO2001053500A1 | 2001-07-26 | |||
| WO2002010217A2 | 2002-02-07 | |||
| WO2000077037A2 | 2000-12-21 |
Other References:
ST CROIX BRAD ET AL: "Genes expressed in human tumor endothelium.", SCIENCE (WASHINGTON D C), vol. 289, no. 5482, 2000, pages 1197 - 1202, XP002216776, ISSN: 0036-8075
MIO H ET AL: "ISOLATION AND CHARACTERIZATION OF A CDNA FOR HUMAN, MOUSE, AND RAT FULL-LENGTH STEM CELL GROWTH FACTOR, A NEW MEMBER OF C-TYPE LECTIN SUPERFAMILY", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 249, no. 1, 1998, pages 124 - 130, XP002076567, ISSN: 0006-291X
CARSON-WALTER ELEANOR B ET AL: "Cell surface tumor endothelial markers are conserved in mice and humans.", CANCER RESEARCH, vol. 61, no. 18, 15 September 2001 (2001-09-15), pages 6649 - 6655, XP002216775, ISSN: 0008-5472
See also references of EP 1345965A2
MIO H ET AL: "ISOLATION AND CHARACTERIZATION OF A CDNA FOR HUMAN, MOUSE, AND RAT FULL-LENGTH STEM CELL GROWTH FACTOR, A NEW MEMBER OF C-TYPE LECTIN SUPERFAMILY", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 249, no. 1, 1998, pages 124 - 130, XP002076567, ISSN: 0006-291X
CARSON-WALTER ELEANOR B ET AL: "Cell surface tumor endothelial markers are conserved in mice and humans.", CANCER RESEARCH, vol. 61, no. 18, 15 September 2001 (2001-09-15), pages 6649 - 6655, XP002216775, ISSN: 0008-5472
See also references of EP 1345965A2
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