Title:
METHODS FOR TREATING DISEASES AND CONDITIONS WITH INVERSE AGONISTS
Document Type and Number:
WIPO Patent Application WO2005034871
Kind Code:
A3
Abstract:
The use of beta-adrenergic inverse agonists provides a new and highly efficient way of treating a number of pulmonary airway diseases, including asthma, emphysema, and chronic obstructive pulmonary diseases. In general, such a method comprises administering a therapeutically effective amount of a beta-adrenergic inverse agonist to the subject to treat the pulmonary airway disease. Particularly preferred inverse agonists include nadolol and carvedilol.
Inventors:
BOND RICHARD A (US)
Application Number:
PCT/US2004/033157
Publication Date:
November 24, 2005
Filing Date:
October 08, 2004
Export Citation:
Assignee:
INVERSEON INC (US)
BOND RICHARD A (US)
BOND RICHARD A (US)
International Classes:
A61K31/137; A61K31/138; A61K31/192; A61K31/403; A61K31/46; A61K31/47; A61K31/522; A61K31/56; A61K; C12N; (IPC1-7): A61K31/138; A61K31/403; A61K31/522; A61K31/137; A61K31/192; A61K31/47; A61K31/46; A61K31/56
Domestic Patent References:
| WO2002036591A2 | 2002-05-10 |
Other References:
DATABASE BIOSIS [online] BOND R.A. ET AL: "Effects of chronic treatment with beta-adrenoceptor antagonist and inverse agonists on a murine model of asthma", XP002989687, accession no. STN Database accession no. PREV200300359094
Download PDF: