Title:
P38α-MK2 INHIBITOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/046327
Kind Code:
A1
Abstract:
Compounds represented by formula I, and racemates, stereoisomers, tautomers, isotope-labeled substances, nitrogen oxides, solvates, polymorphs, pharmaceutically acceptable salts or prodrugs thereof. The compounds have a good inhibition effect on p38α-MK2 and can be therefore used for treating or preventing p38α-MK2 related symptoms and diseases and for preparing drugs for treating or preventing such symptoms and diseases.
Inventors:
YANG FANGLONG (CN)
HUANG YUE (CN)
FU DONGLIN (CN)
YU LITING (CN)
FAN JINGRONG (CN)
WANG SIQIN (CN)
JIN LEI (CN)
HUANG YUE (CN)
FU DONGLIN (CN)
YU LITING (CN)
FAN JINGRONG (CN)
WANG SIQIN (CN)
JIN LEI (CN)
Application Number:
PCT/CN2023/115579
Publication Date:
March 07, 2024
Filing Date:
August 29, 2023
Export Citation:
Assignee:
CHANGCHUN GENESCIENCE PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D401/14; A61K31/506; A61K31/5377; A61P3/00; A61P35/00; A61P37/06; C07D405/14
Domestic Patent References:
| WO2023125707A1 | 2023-07-06 | |||
| WO2023125708A1 | 2023-07-06 | |||
| WO2022212489A1 | 2022-10-06 | |||
| WO2013105676A1 | 2013-07-18 |
Foreign References:
| CN115636814A | 2023-01-24 | |||
| CN103391718A | 2013-11-13 | |||
| CN105263326A | 2016-01-20 | |||
| US20130274272A1 | 2013-10-17 | |||
| US20130143906A1 | 2013-06-06 |
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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