Title:
MODULATION OF NOTCH3 EXPRESSION
Document Type and Number:
WIPO Patent Application WO2004047731
Kind Code:
A8
Abstract:
Compounds, compositions and methods are provided for modulating the expression of Notch3. The compositions comprise oligonucleotides, targeted to nucleic acid encoding Notch3. Methods of using these compounds for modulation of Notch3 expression and for diagnosis and treatment of disease associated with expression of Notch3 are provided.
Inventors:
FREIER SUSAN M (US)
DOBIE KENNETH W (US)
DOBIE KENNETH W (US)
Application Number:
PCT/US2003/036961
Publication Date:
September 16, 2004
Filing Date:
November 19, 2003
Export Citation:
Assignee:
ISIS PHARMACEUTICALS INC (US)
FREIER SUSAN M (US)
DOBIE KENNETH W (US)
FREIER SUSAN M (US)
DOBIE KENNETH W (US)
International Classes:
C12N5/02; C12N15/113; C12Q1/68; A61K38/00; (IPC1-7): A61K/
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