Title:
MOLECULARLY IMPRINTED POLYMER BASED SENSORS FOR THE DETECTION OF NARCOTICS
Document Type and Number:
WIPO Patent Application WO2001077672
Kind Code:
A3
Abstract:
A device for measuring and detecting at least one narcotic, such as heroin and cocaine, in a fluid is provided. The device functions by selectively binding vapors of a narcotic or a narcotic present in a liquid, e.g., blood, to a luminescent molecularly imprinted polymer. The polymer possesses a securely bound luminescent lanthanide ion, such as Eu<3+>, in a coordination complex that has been templated with a narcotic.
Inventors:
MURRAY GEORGE M (US)
Application Number:
PCT/US2001/011694
Publication Date:
November 07, 2002
Filing Date:
April 10, 2001
Export Citation:
Assignee:
UNIV JOHNS HOPKINS (US)
MURRAY GEORGE M (US)
MURRAY GEORGE M (US)
International Classes:
G01N21/77; G01N29/02; G01N31/22; G01N33/02; G01N33/00; (IPC1-7): G01N21/77; G01N33/487; G01N33/00
Foreign References:
| US5864397A | 1999-01-26 |
Other References:
JENKINS A L ET AL: "POLYMER-BASED LANTHANIDE LUMINESCENT SENSOR FOR DETECTION OF THE HYDROLYSIS PRODUCT OF THE NERVE AGENT SOMAN IN WATER", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 71, no. 2, 15 January 1999 (1999-01-15), pages 373 - 378, XP000825699, ISSN: 0003-2700
D.KRIZ,O.RAMSTEIN, K. MOSBACH: "Molecular imprinting-based biomimetic sensors could provide an alternative to often unstable biosensors for industry, medicine, and environmental analysis", ANALYTICAL CHEMISTRY, 1 June 1997 (1997-06-01), pages 1 - 5, XP002191157, Retrieved from the Internet [retrieved on 20020222]
F.L. DICKERT ET AL: "Molecular imprinting in chemical sensing - Detection of aromatic and halogenated hydrocarbons as well as polar solvent vapors", FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, vol. 360, 1998, pages 759 - 762, XP002202443, Retrieved from the Internet [retrieved on 20020617]
ANONYMOUS: "10. MIPS", INTERNET ARTICLE, 31 July 1998 (1998-07-31), pages 1 - 4, XP002202444, Retrieved from the Internet [retrieved on 20020617]
CHENGDU LIANG ET AL: "Bulk acoustic wave sensor for herbicide assay based on molecularly imprinted polymer.", FRESENIUS' JOURNAL OF ANALYTICAL CHEMISTRY 367 (6) 551-555 2000 COLL. OF CHEM. & CHEM. ENG., HUNAN UNIV., CHANGSHA 410082, CHINA. E-MAIL SZYAO(A)MAIL.HUNU.EDU.CN, vol. 367, 3 July 2000 (2000-07-03), pages 551 - 555, XP008000976, Retrieved from the Internet [retrieved on 20020222]
HAUPT K ET AL: "MOLECULARLY IMPRINTED POLYMERS AND THEIR USE IN BIOMIMETIC SENSORS", CHEMICAL REVIEWS, AMERICAN CHEMICAL SOCIETY. EASTON, US, vol. 100, no. 7, 12 July 2000 (2000-07-12), pages 2495 - 2504, XP001064939, ISSN: 0009-2665
D.KRIZ,O.RAMSTEIN, K. MOSBACH: "Molecular imprinting-based biomimetic sensors could provide an alternative to often unstable biosensors for industry, medicine, and environmental analysis", ANALYTICAL CHEMISTRY, 1 June 1997 (1997-06-01), pages 1 - 5, XP002191157, Retrieved from the Internet
F.L. DICKERT ET AL: "Molecular imprinting in chemical sensing - Detection of aromatic and halogenated hydrocarbons as well as polar solvent vapors", FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, vol. 360, 1998, pages 759 - 762, XP002202443, Retrieved from the Internet
ANONYMOUS: "10. MIPS", INTERNET ARTICLE, 31 July 1998 (1998-07-31), pages 1 - 4, XP002202444, Retrieved from the Internet
CHENGDU LIANG ET AL: "Bulk acoustic wave sensor for herbicide assay based on molecularly imprinted polymer.", FRESENIUS' JOURNAL OF ANALYTICAL CHEMISTRY 367 (6) 551-555 2000 COLL. OF CHEM. & CHEM. ENG., HUNAN UNIV., CHANGSHA 410082, CHINA. E-MAIL SZYAO(A)MAIL.HUNU.EDU.CN, vol. 367, 3 July 2000 (2000-07-03), pages 551 - 555, XP008000976, Retrieved from the Internet
HAUPT K ET AL: "MOLECULARLY IMPRINTED POLYMERS AND THEIR USE IN BIOMIMETIC SENSORS", CHEMICAL REVIEWS, AMERICAN CHEMICAL SOCIETY. EASTON, US, vol. 100, no. 7, 12 July 2000 (2000-07-12), pages 2495 - 2504, XP001064939, ISSN: 0009-2665
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