Title:
NIMESULIDE TOPICAL FORMULATIONS IN THE FORM OF LIQUID CRYSTALS
Document Type and Number:
WIPO Patent Application WO1998037868
Kind Code:
A3
Abstract:
Nimesulide topical formulations are provided in the form of liquid crystals. The emulsifier cetylstearyl glycoside is used, and constituents of the lipid phase such as caprylic/capric triglycerides and jojoba oil, consistence factors such as cetylstearyl alcohol. Also disclosed is a process for the preparation thereof. The formulations have advantages such as higher stability, better release and absorption of nimesulide, and a higher bioavailability of the active ingredient.
Inventors:
BADER STEFANO (IT)
HAEUSERMANN ENRIQUE (IT)
MONTI TIZIANA (IT)
HAEUSERMANN ENRIQUE (IT)
MONTI TIZIANA (IT)
Application Number:
PCT/EP1998/000896
Publication Date:
December 10, 1998
Filing Date:
February 17, 1998
Export Citation:
Assignee:
HELSINN HEALTHCARE SA (CH)
BADER STEFANO (CH)
HAEUSERMANN ENRIQUE (CH)
MONTI TIZIANA (CH)
BADER STEFANO (CH)
HAEUSERMANN ENRIQUE (CH)
MONTI TIZIANA (CH)
International Classes:
A61K9/127; A61K31/18; (IPC1-7): A61K9/107; A61K31/18
Foreign References:
| EP0782855A1 | 1997-07-09 | |||
| DE4320119A1 | 1994-12-22 | |||
| EP0087062A2 | 1983-08-31 |
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