Title:
NOVEL 4-SUBSTITUTED OXAZOLOQUINOLINONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASES INCLUDING ASTHMA OR ATOPIC DERMATITIS COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2020/009374
Kind Code:
A1
Abstract:
The present invention relates to a 4-substituted oxazoloquinolinone derivative, and a compound, which is a salt of the derivative, that show effects of preventing and treating allergic diseases, such as asthma or atopic dermatitis, by controlling intracellular signal transduction due to IL-33. The derivative and the compound of the present invention can effectively suppress the formation of inflammatory reactions of allergic diseases, such as asthma or atopic dermatitis, and thus, a pharmaceutical composition comprising the derivative and the compound can be used to fundamentally prevent or treat various allergies and asthmatic diseases.
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Inventors:
BYUN YOUNGJOO (KR)
JEON YOUNG HO (KR)
LEE KIHO (KR)
LEE KI YONG (KR)
JUNG YONG WOO (KR)
SON SANG-HYUN (KR)
JEON YOUNG HO (KR)
LEE KIHO (KR)
LEE KI YONG (KR)
JUNG YONG WOO (KR)
SON SANG-HYUN (KR)
Application Number:
PCT/KR2019/007822
Publication Date:
January 09, 2020
Filing Date:
June 27, 2019
Export Citation:
Assignee:
UNIV KOREA RES & BUSINESS FOUNDATION SEJONG CAMPUS (KR)
International Classes:
C07D498/04; A61K31/4738; A61K31/4745; A61P11/02; A61P17/00; A61P37/00
Domestic Patent References:
| WO2016136727A1 | 2016-09-01 | |||
| WO2018128407A1 | 2018-07-12 |
Foreign References:
| KR101839721B1 | 2018-03-16 | |||
| US5182290A | 1993-01-26 | |||
| KR100919147B1 | 2009-09-25 |
Attorney, Agent or Firm:
JUNG, Eun Youl (KR)
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