Title:
NOVEL ACYLAMINO-SUBSTITUTED ACYLANILIDE DERIVATIVES OR PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
Document Type and Number:
WIPO Patent Application WO/1998/022432
Kind Code:
A1
Abstract:
Acylamino-substituted acylanilide derivatives represented by general formula (I) or salts thereof, and a pharmaceutical composition comprising the same. They have an antiandrogenic activity and are useful as a prophylactic or therapeutic agent for prostatic cancer, prostatic hypertrophy, defemination, hypertrichosis, bald head, acne, seborrhea and the like in which androgen is involved as an exacerbating factor.
Inventors:
TANIGUCHI NOBUAKI (JP)
OKADA MINORU (JP)
KAKU HIDETAKA (JP)
SHIMADA ITSURO (JP)
NOZAWA EISUKE (JP)
KOUTOKU HIROSHI (JP)
OKADA MINORU (JP)
KAKU HIDETAKA (JP)
SHIMADA ITSURO (JP)
NOZAWA EISUKE (JP)
KOUTOKU HIROSHI (JP)
Application Number:
PCT/JP1997/004174
Publication Date:
May 28, 1998
Filing Date:
November 17, 1997
Export Citation:
Assignee:
YAMANOUCHI PHARMA CO LTD (JP)
TANIGUCHI NOBUAKI (JP)
OKADA MINORU (JP)
KAKU HIDETAKA (JP)
SHIMADA ITSURO (JP)
NOZAWA EISUKE (JP)
KOUTOKU HIROSHI (JP)
TANIGUCHI NOBUAKI (JP)
OKADA MINORU (JP)
KAKU HIDETAKA (JP)
SHIMADA ITSURO (JP)
NOZAWA EISUKE (JP)
KOUTOKU HIROSHI (JP)
International Classes:
C07C255/60; C07C311/06; C07C311/13; C07C311/19; C07C311/29; C07C327/42; C07C327/48; C07D205/04; C07D207/16; C07D207/34; C07D209/08; C07D209/42; C07D211/34; C07D213/81; C07D213/82; C07D215/36; C07D215/48; C07D217/26; C07D239/28; C07D307/68; C07D309/14; C07D309/38; C07D333/34; C07D333/38; C07D333/68; C07D335/02; (IPC1-7): C07C237/22; A61K31/165; A61K31/275; A61K31/34; A61K31/35; A61K31/38; A61K31/395; A61K31/40; A61K31/44; A61K31/47; C07C255/60; C07C275/28; C07C311/06; C07C311/19; C07C327/42; C07C327/48; C07C335/26; C07D205/04; C07D207/14; C07D207/16; C07D207/48; C07D209/08; C07D209/30; C07D209/36; C07D213/81; C07D215/36; C07D217/22; C07D241/12; C07D241/14; C07D307/64; C07D309/38; C07D333/34; C07D333/38; C07D333/70; C07D335/02
Foreign References:
| US4532251A | 1985-07-30 | |||
| JPS4981332A | 1974-08-06 |
Other References:
CHEMICAL ABSTRACTS, Vol. 101, 1984, Abstract No. 6764, VIEWEG H., "Synthesis of alpha-(Arylsulfonylamino)-Omega-Phenylalkyl carboxylic Acid 3- and -4-Amidinoanilides"; & PHARMAZIE, 1983, 38(12), 818-20.
Attorney, Agent or Firm:
Nagai, Shozo (Patent & Information Dept., 17-1, Hasune 3-chom, Itabashi-ku Tokyo, JP)
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