Title:
NOVEL AMINES AND THEIR USE
Document Type and Number:
WIPO Patent Application WO/1989/005289
Kind Code:
A1
Abstract:
Amines represented by general formula (1) and acid addition salts and quaternary ammonium salts thereof are disclosed. The amines represented by formula (1) or pharmaceutically acceptable acid addition salts and quaternary ammonium salts thereof are useful for treatment and prophylaxis of heart diseases of animals, particularly arrhythmia, myocardial infarction, angina pectoris, cardiac failure, etc.
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Inventors:
TOMINO IKUO (JP)
ISHIGURO MASAHARU (JP)
KITAHARA TAKUMI (JP)
YOKOYAMA KEIICHI (JP)
KIHARA NORIAKI (JP)
KAMIYA JOJI (JP)
YOSHIHARA KANJI (JP)
ISHII MASAAKI (JP)
MIZUCHI AKIRA (JP)
HORIKOMI KAZUTOSHI (JP)
AWAYA AKIRA (JP)
NAKANO TAKUO (JP)
ISHIGURO MASAHARU (JP)
KITAHARA TAKUMI (JP)
YOKOYAMA KEIICHI (JP)
KIHARA NORIAKI (JP)
KAMIYA JOJI (JP)
YOSHIHARA KANJI (JP)
ISHII MASAAKI (JP)
MIZUCHI AKIRA (JP)
HORIKOMI KAZUTOSHI (JP)
AWAYA AKIRA (JP)
NAKANO TAKUO (JP)
Application Number:
PCT/JP1988/001240
Publication Date:
June 15, 1989
Filing Date:
December 09, 1988
Export Citation:
Assignee:
MITSUI PETROCHEMICAL IND (JP)
MITSUI PHARMACEUTICALS (JP)
MITSUI PHARMACEUTICALS (JP)
International Classes:
A61K31/34; A61K31/35; C07C217/18; C07C217/22; C07C217/32; C07D209/08; C07D209/48; C07D211/14; C07D215/04; C07D217/02; C07D217/24; C07D235/06; C07D265/36; C07D307/78; C07D307/79; C07D307/80; C07D307/83; C07D307/86; C07D307/91; C07D311/04; C07D311/08; C07D311/14; C07D311/16; C07D311/18; C07D311/20; C07D311/22; C07D311/24; C07D311/58; C07D311/74; C07D317/06; C07D317/46; C07D317/48; C07D327/04; C07D401/12; C07D405/12; C07D407/12; C07D471/10; C07D487/04; C07D487/22; C07D491/10; (IPC1-7): C07C93/06; C07C93/14; C07C93/26; C07C143/75; C07C143/78; C07C153/00; C07D209/48; C07D307/78; C07D307/91; C07D311/74; C07D317/46; C07D327/04; A61K31/135; A61K31/34; A61K31/35; A61K31/36; A61K31/38; A61K31/40
Foreign References:
| JPS60258174A | 1985-12-20 | |||
| JPS60209551A | 1985-10-22 | |||
| JPH05740479A | ||||
| JPS62502463A | 1987-09-24 | |||
| JPH06143184A | 1994-05-24 | |||
| JPS57144278A | 1982-09-06 | |||
| JPH05368775A | ||||
| JPH05919106B | ||||
| JPS51125334A | 1976-11-01 | |||
| JPS51131838A | 1976-11-16 | |||
| JPH04951254A | ||||
| JPH04849755A | ||||
| JPS479972A |
Other References:
Journal of Medicinal Chemistry, Vol. 18, No. 2, (1975), MILTON L. HOEFLE et al., Cardioselective beta-Adrenergic Blocking Agents. 1. 1 - (3,4-Dimethoxyphenethyl)-Amino)-3-Aryloxy-2-Propanols, pp. 148-152, especially, see p. 151
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