Title:
NOVEL ANTI-FGFR2B ANTIBODIES
Document Type and Number:
WIPO Patent Application WO/2021/129656
Kind Code:
A1
Abstract:
Provided are anti-FGFR2b antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.
Inventors:
WANG MEI (CN)
GUO QIULI (CN)
BAI YU (CN)
YANG ZHENFAN (CN)
ZHANG XIAOLIN (CN)
GUO QIULI (CN)
BAI YU (CN)
YANG ZHENFAN (CN)
ZHANG XIAOLIN (CN)
Application Number:
PCT/CN2020/138591
Publication Date:
July 01, 2021
Filing Date:
December 23, 2020
Export Citation:
Assignee:
DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN)
International Classes:
C07K16/00; C12N1/21
Foreign References:
| CN110402254A | 2019-11-01 | |||
| CN107108740A | 2017-08-29 | |||
| US20100047251A1 | 2010-02-25 | |||
| CN104066750A | 2014-09-24 |
Other References:
DANIEL VT CATENACCI, ANTENEH TESFAYE, MOHAMED TEJANI, ERIC CHEUNG, PETER EISENBERG, AARON J SCOTT, CLARENCE ENG, JAMES HNATYSZYN, : "Bemarituzumab with modified FOLFOX6 for advanced FGFR2-positive gastroesophageal cancer: FIGHT Phase III study design.", FUTURE ONCOLOGY, vol. 15, no. 18, 16 May 2019 (2019-05-16), pages 2073 - 2082, XP055823774, ISSN: 1479-6694, DOI: 10.2217/fon-2019-0141
DATABASE Protein 16 October 2017 (2017-10-16), ANONYMOUS: "immunoglobulin heavy chain variable region,partial [Mus musculus]", XP055823779, retrieved from NCbi Database accession no. ATI98012
DATABASE Protein 1 December 2020 (2020-12-01), ANONYMOUS: "Chain L, 5F6 LIGHT CHAIN", XP055823786, retrieved from NCBI Database accession no. 3NZH_L
DATABASE Protein 16 October 2017 (2017-10-16), ANONYMOUS: "immunoglobulin heavy chain variable region, partial [Mus musculus]", XP055823793, retrieved from NCBI Database accession no. ATI97941
DATABASE Protein 10 March 2016 (2016-03-10), ANONYMOUS: "immunoglobulin heavy chain variable region, partial [Mus musculus]", XP055823797, retrieved from NCBI Database accession no. AML31184
DATABASE Protein 10 March 2016 (2016-03-10), ANONYMOUS: "immunoglobulin heavy chain variable region, partial [Mus musculus]", XP055823801, retrieved from NCBI Database accession no. AML31151
DATABASE Protein 9 February 1995 (1995-02-09), ANONYMOUS: "anti-alpha 4 integrin immunoglobulin kappa chain V region, partial [Mus musculus]", XP055823811, retrieved from NCBI Database accession no. AAA62143
DATABASE Protein 20 February 2018 (2018-02-20), ANONYMOUS: "immunoglobulin light chain, partial [Mus musculus]", XP055823816, retrieved from NCBI Database accession no. AVD98668
DATABASE Protein 26 July 2016 (2016-07-26), ANONYMOUS: "immunoglobulin light chain, partial [Mus musculus]", XP055823821, retrieved from NCBI Database accession no. CAI30334
See also references of EP 4081539A4
DATABASE Protein 16 October 2017 (2017-10-16), ANONYMOUS: "immunoglobulin heavy chain variable region,partial [Mus musculus]", XP055823779, retrieved from NCbi Database accession no. ATI98012
DATABASE Protein 1 December 2020 (2020-12-01), ANONYMOUS: "Chain L, 5F6 LIGHT CHAIN", XP055823786, retrieved from NCBI Database accession no. 3NZH_L
DATABASE Protein 16 October 2017 (2017-10-16), ANONYMOUS: "immunoglobulin heavy chain variable region, partial [Mus musculus]", XP055823793, retrieved from NCBI Database accession no. ATI97941
DATABASE Protein 10 March 2016 (2016-03-10), ANONYMOUS: "immunoglobulin heavy chain variable region, partial [Mus musculus]", XP055823797, retrieved from NCBI Database accession no. AML31184
DATABASE Protein 10 March 2016 (2016-03-10), ANONYMOUS: "immunoglobulin heavy chain variable region, partial [Mus musculus]", XP055823801, retrieved from NCBI Database accession no. AML31151
DATABASE Protein 9 February 1995 (1995-02-09), ANONYMOUS: "anti-alpha 4 integrin immunoglobulin kappa chain V region, partial [Mus musculus]", XP055823811, retrieved from NCBI Database accession no. AAA62143
DATABASE Protein 20 February 2018 (2018-02-20), ANONYMOUS: "immunoglobulin light chain, partial [Mus musculus]", XP055823816, retrieved from NCBI Database accession no. AVD98668
DATABASE Protein 26 July 2016 (2016-07-26), ANONYMOUS: "immunoglobulin light chain, partial [Mus musculus]", XP055823821, retrieved from NCBI Database accession no. CAI30334
See also references of EP 4081539A4
Attorney, Agent or Firm:
JUN HE LAW OFFICES (CN)
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