Title:
NOVEL CYCLIC SQUARAMIDE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2011/034051
Kind Code:
A1
Abstract:
Compounds represented by general formula (1) or salts thereof. In general formula (1), A is an aromatic hydrocarbon ring or an aromatic heterocycle (with the ring and the heterocycle being optionally substituted); R1 to R11 may be the same or different and are each a hydrogen atom, a halogen atom, hydroxyl, mercapto, amino, or the like; R1 and R2 may be united to form a hydrocarbon ring or a heterocycle (with the ring and the heterocycle being optically substituted); X1 and X2 may be the same or different and are each an oxygen atom, a sulfur atom, or NR3; Y is CO, CS, CNR4, -CR5R6-, -CR5R6CR7R8-, or CR5R6CR7R8CR9R10-; one of R5 to R10 together with R3 may form an optionally substituted heterocycle; Z is a chalcogen atom or NR11; and the broken line represents a single bond or a double bond.
Inventors:
HONDA TAKAHIRO (JP)
SETOGUCHI CHIKAKO (JP)
MOGI HIROYUKI (JP)
TSUJI FUMIO (JP)
AONO HIROYUKI (JP)
BAN MASAKAZU (JP)
SETOGUCHI CHIKAKO (JP)
MOGI HIROYUKI (JP)
TSUJI FUMIO (JP)
AONO HIROYUKI (JP)
BAN MASAKAZU (JP)
Application Number:
PCT/JP2010/065821
Publication Date:
March 24, 2011
Filing Date:
September 14, 2010
Export Citation:
Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
HONDA TAKAHIRO (JP)
SETOGUCHI CHIKAKO (JP)
MOGI HIROYUKI (JP)
TSUJI FUMIO (JP)
AONO HIROYUKI (JP)
BAN MASAKAZU (JP)
HONDA TAKAHIRO (JP)
SETOGUCHI CHIKAKO (JP)
MOGI HIROYUKI (JP)
TSUJI FUMIO (JP)
AONO HIROYUKI (JP)
BAN MASAKAZU (JP)
International Classes:
C07D245/04; A61K31/395; A61K31/407; A61K31/4353; A61K31/4365; A61K31/496; A61K31/5377; A61P3/04; A61P3/14; A61P9/06; A61P9/10; A61P9/12; A61P25/02; A61P25/08; A61P25/18; A61P27/06; A61P29/00; A61P43/00; C07D267/22; C07D281/18; C07D498/06; C07D513/04; C07D513/06
Domestic Patent References:
| WO2008143263A1 | 2008-11-27 |
Foreign References:
| JPH10237073A | 1998-09-08 |
Other References:
PEI Y ET AL.: "Efficient Syntheses of Benzothiazepines as Antagonists for the Mitochondrial Sodium-Calcium Exchanger: Potential Therapeutics for Type II Diabetes", JOURNAL OF ORGANIC CHEMISTRY, vol. 68, 2003, pages 92 - 103
Attorney, Agent or Firm:
Fukami Patent Office, p. c. (JP)
Patent business corporation Fukami patent firm (JP)
Patent business corporation Fukami patent firm (JP)
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