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Title:
NOVEL GLYCOSYLATED POLYPEPTIDES
Document Type and Number:
WIPO Patent Application WO/2012/012271
Kind Code:
A3
Abstract:
Provided herein are glycosylated polypeptide compositions with substantially reduced Neu5Gc content. The glycosylated polypeptides compositions with substantially reduced Neu5Gc content can be obtained from cell sources cultured with Neu5Gc competitor or from non-human animal sources fed a diet supplemented with Neu5Gc competitor. Also provided herein are methods of treating a human subject with said compositions.

Inventors:
VARKI AJIT (US)
GHADERI DARIUS (US)
Application Number:
PCT/US2011/044081
Publication Date:
March 27, 2014
Filing Date:
July 14, 2011
Export Citation:
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Assignee:
SIALIX INC (US)
VARKI AJIT (US)
GHADERI DARIUS (US)
International Classes:
C12N5/07; A61K39/00; C12N5/16; C12P21/08
Domestic Patent References:
WO2010030666A22010-03-18
Foreign References:
US20090099073A12009-04-16
Attorney, Agent or Firm:
WARD, Donna T. (292 Main Street Suite, Groton MA, US)
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