Title:
NOVEL A-LIPOIC ACID DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2002/076935
Kind Code:
A1
Abstract:
A novel a-lipoic acid derivative represented by the following formula (I). It has tyrosinase inhibitory activity, melanin production inhibitory activity, and elastase inhibitory activity. (I) (In the formula, M represents a metal and A represents an amino acid residue bonded through the nitrogen atom.).
Inventors:
OGATA KAZUMI (JP)
SAKAUE TAKAHIRO (JP)
ITO KAZUHIKO (JP)
SAKAUE TAKAHIRO (JP)
ITO KAZUHIKO (JP)
Application Number:
PCT/JP2002/002577
Publication Date:
October 03, 2002
Filing Date:
March 18, 2002
Export Citation:
Assignee:
SENJU PHARMA CO (JP)
OGATA KAZUMI (JP)
SAKAUE TAKAHIRO (JP)
ITO KAZUHIKO (JP)
OGATA KAZUMI (JP)
SAKAUE TAKAHIRO (JP)
ITO KAZUHIKO (JP)
International Classes:
A61K31/185; A61K31/195; A61K31/197; A61K31/198; A61K41/00; A61P17/16; A61P43/00; C07C323/60; (IPC1-7): C07C323/60; A61K7/00; A61K7/42; A61K31/185; A61K31/195; A61K31/197; A61K31/198; A61P17/16; A61P43/00
Domestic Patent References:
WO2000020385A1 | 2000-04-13 | |||
WO1995008564A1 | 1995-03-30 | |||
WO2000032235A1 | 2000-06-08 |
Foreign References:
JPS638316A | 1988-01-14 |
Other References:
JUN OIZUMI, KOU HAYAKAWA: "Lipoamidase is a multiple hydrolase", BIOCHEMICAL JOURNAL, vol. 271, no. 1, 1990, pages 45 - 49, XP002953518
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