Title:
NOVEL NORSTATIN DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2003/018542
Kind Code:
A1
Abstract:
A norstatin derivative represented by the following general formula (I) or a salt thereof, which are useful as an intermediate for medicines, e.g., HIV protease inhibitors, bestatin and taxol as carcinostatic agents, and renin inhibitors. (I) In the formula, R1 and R2 each represents C3 or lower alkoxy or R1 and R2 in combination may form a ring&semi R3 and R4 each represents hydrogen, optionally substituted benzyl, C4 or lower acyl, optionally substituted C14 or lower alkoxycarbonyl or aralkyloxycarbonyl, or optionally substituted benzoyl or benzenesulfonyl or R3 and R4 in combination may form a ring&semi R5 represents hydrogen or C4 or lower acyl&semi and R6 represents hydrogen, C4 or lower alkyl, or C14 or lower aralkyl.
Inventors:
NOJIMA SATOSHI (JP)
MIMOTO TSUTOMU (JP)
MIMOTO TSUTOMU (JP)
Application Number:
PCT/JP2002/006094
Publication Date:
March 06, 2003
Filing Date:
June 19, 2002
Export Citation:
Assignee:
JAPAN ENERGY CORP (JP)
NOJIMA SATOSHI (JP)
MIMOTO TSUTOMU (JP)
NOJIMA SATOSHI (JP)
MIMOTO TSUTOMU (JP)
International Classes:
A61K31/216; A61K31/27; A61K31/427; A61P31/18; A61P43/00; C07C271/22; C07D317/60; C07D417/06; (IPC1-7): C07C271/22; A61K31/216; A61K31/27; A61K31/427; A61P31/18; A61P43/00; C07D317/60; C07D417/06
Domestic Patent References:
| WO1994000420A1 | 1994-01-06 |
Foreign References:
| JPS5686142A | 1981-07-13 | |||
| GB2037754A | 1980-07-16 | |||
| EP1157997A1 | 2001-11-28 |
Attorney, Agent or Firm:
Fujino, Seiya (2-1 Yotsuya 1-chom, Shinjuku-ku Tokyo, JP)
Download PDF: