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Title:
A NOVEL POLYPEPTIDE - NAD-DEPENDENT 2-HYDROXY ACID DEHYDROGENASE FAMILY PROTEIN 9 AND THE POLYNUCLEOTIDE ENCODING SAID POLYPEPTIDE
Document Type and Number:
WIPO Patent Application WO/2001/046234
Kind Code:
A1
Abstract:
The invention disclosed a new kind of polypeptide-NAD-dependent 2-hydroxy acid dehydrogenase family protein 9 and the polynucleotide encoding said polypeptide and a process for producing the polypeptide by recombinant methods. It also disclosed the method of applying the polypeptide for the treatment of various kinds of diseases, such as cancer, hemopathy, HIV infection, immune diseases and inflammation. The antagonist of the polypeptide and therapeutic use of the same is also disclosed. In addition, it refers to the use of polynucleotide encoding said NAD-dependent 2-hydroxy acid dehydrogenase family protein 9.

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Inventors:
MAO YUMIN (CN)
XIE YI (CN)
Application Number:
PCT/CN2000/000566
Publication Date:
June 28, 2001
Filing Date:
December 11, 2000
Export Citation:
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Assignee:
UNIV FUDAN (CN)
BIODOOR GENE TECH LTD SHANGHAI (CN)
MAO YUMIN (CN)
XIE YI (CN)
International Classes:
C12N9/04; (IPC1-7): C07K14/435; A61K38/17
Foreign References:
US5965372A1999-10-12
US5883240A1999-03-16
Attorney, Agent or Firm:
SHANGHAI ZHI XIN PATENT AGENT LTD. (Italy Building 446 Zhao Jia Bang Road, Shanghai 1, CN)
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