Title:
NOVEL PROTEIN VARIANT AND METHOD FOR PRODUCING L-VALINE USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/163925
Kind Code:
A1
Abstract:
The present application relates to a novel protein variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
Inventors:
PARK GOUN (KR)
KIM SEON HYE (KR)
YOON BYOUNG HOON (KR)
BAE JEE YEON (KR)
KIM HYO JIN (KR)
KIM HYUNG JOON (KR)
KIM SEON HYE (KR)
YOON BYOUNG HOON (KR)
BAE JEE YEON (KR)
KIM HYO JIN (KR)
KIM HYUNG JOON (KR)
Application Number:
PCT/KR2021/004520
Publication Date:
August 04, 2022
Filing Date:
April 09, 2021
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C07K14/34; C12N15/77; C12P13/08
Domestic Patent References:
| WO2020016604A1 | 2020-01-23 |
Foreign References:
| KR20160017389A | 2016-02-16 | |||
| CN110982772A | 2020-04-10 | |||
| KR101117022B1 | 2012-03-16 | |||
| US8465962B2 | 2013-06-18 | |||
| US7662943B2 | 2010-02-16 | |||
| US10584338B2 | 2020-03-10 | |||
| US10273491B2 | 2019-04-30 |
Other References:
DATABASE Protein [https://www.ncbi.nlm.nih.gov/protein/AST20676.1] 10 August 2017 (2017-08-10), "3-methyladenine DNA glycosylase [Corynebacterium glutamicum ATCC 14067", XP055909893, retrieved from NCBI Database accession no. AST20676.1
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
GENE, vol. 145, 1994, pages 69 - 73
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
J. SAM BROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI, vol. 50-51, no. 2, 2014, pages 2773 - 2793
SAMBROOK ET AL., MOLECULAR CLONING, 2012
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
See also references of EP 4059953A4
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
GENE, vol. 145, 1994, pages 69 - 73
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
J. SAM BROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI, vol. 50-51, no. 2, 2014, pages 2773 - 2793
SAMBROOK ET AL., MOLECULAR CLONING, 2012
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
See also references of EP 4059953A4
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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