Title:
NOVEL TUMOR ANTIGEN PROTEIN SART-3 AND TUMOR ANTIGEN PEPTIDE THEREOF
Document Type and Number:
WIPO Patent Application WO/2000/012701
Kind Code:
A1
Abstract:
A novel tumor antigen protein; its gene; a tumor antigen peptide derived from this tumor antigen protein; derivatives of these substances; and remedies, preventives, diagnostics, etc. for tumor with the use of these substances $i(in vivo) or $i(in vitro).
Inventors:
ITOH KYOGO (JP)
NAKAO MASANOBU (JP)
NAKAO MASANOBU (JP)
Application Number:
PCT/JP1999/004622
Publication Date:
March 09, 2000
Filing Date:
August 27, 1999
Export Citation:
Assignee:
SUMITOMO PHARMA (JP)
ITOH KYOGO (JP)
NAKAO MASANOBU (JP)
ITOH KYOGO (JP)
NAKAO MASANOBU (JP)
International Classes:
C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/07; C12N5/0783; C12N5/09; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12Q1/02; G01N33/574; A61K38/00; (IPC1-7): C12N15/12; C12N5/10; C12P21/02; C07K14/47; C07K16/30; A61K31/70; A61K48/00; A61K38/17; A61K39/00; A61K35/12
Other References:
SHIGEKI SHICHIJO ET AL.: "A Gene Encoding Antigenic Peptides of Human Squamous Cell Carcinoma Recognized by Cytotoxic T Lymphocytes", J. EXP. MED., vol. 187, no. 3, 2 February 1998 (1998-02-02), pages 277 - 288, XP002932468
RUMI GOHARA: "Histocompatibility Leukocyte Antigen-A2402-restricted Cytotoxic T Lymphocytes Recognizing Adenocarcinoma in Tumor-infiltrating Lymphocytes of Patients with Coiono Cancer", JPN. J. CANCER RES., vol. 88, no. 2, February 1997 (1997-02-01), pages 198 - 204, XP002932469
TAKAHIRO NAGASE: "Prediction of the Coding Sequences of Unidentified Human Genes. IV. The Coding Sequences of 40 New Genes (KIAA0121-KIAA0160) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1", J. CLIN. INVEST., vol. 2, no. 4, August 1995 (1995-08-01), pages 167 - 174, XP002932470
P. YOTNDA: "Cytotoxic T Cell Response against the Chimeric ETV6-AML1 Protein in Childhood Acute Lymphoblastic Leukemia", J. CLIN. INVEST., vol. 102, no. 2, July 1998 (1998-07-01), pages 455 - 462, XP002932471
TAKENORI TAKAHASHI: "Recognition of gp43 Tumor-Associated Antigen Peptide by both HLA-A2 Restricted CTL Lines and Antibodies from Melanoma Patients", CELLULAR IMMUNOLOGY, vol. 178, no. 2, 15 June 1997 (1997-06-15), pages 162 - 171, XP002932472
RUMI GOHARA: "Histocompatibility Leukocyte Antigen-A2402-restricted Cytotoxic T Lymphocytes Recognizing Adenocarcinoma in Tumor-infiltrating Lymphocytes of Patients with Coiono Cancer", JPN. J. CANCER RES., vol. 88, no. 2, February 1997 (1997-02-01), pages 198 - 204, XP002932469
TAKAHIRO NAGASE: "Prediction of the Coding Sequences of Unidentified Human Genes. IV. The Coding Sequences of 40 New Genes (KIAA0121-KIAA0160) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1", J. CLIN. INVEST., vol. 2, no. 4, August 1995 (1995-08-01), pages 167 - 174, XP002932470
P. YOTNDA: "Cytotoxic T Cell Response against the Chimeric ETV6-AML1 Protein in Childhood Acute Lymphoblastic Leukemia", J. CLIN. INVEST., vol. 102, no. 2, July 1998 (1998-07-01), pages 455 - 462, XP002932471
TAKENORI TAKAHASHI: "Recognition of gp43 Tumor-Associated Antigen Peptide by both HLA-A2 Restricted CTL Lines and Antibodies from Melanoma Patients", CELLULAR IMMUNOLOGY, vol. 178, no. 2, 15 June 1997 (1997-06-15), pages 162 - 171, XP002932472
Attorney, Agent or Firm:
Aoyama, Tamotsu (IMP Building 3-7, Shiromi 1-chome, Chuo-k, Osaka-shi Osaka, JP)
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