OSTEOCLASTOGENESIS INHIBITORS AND USES THEREOF

Title:

OSTEOCLASTOGENESIS INHIBITORS AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO2006046934

Kind Code:

A3

Abstract:

The present invention provides a method of reducing or inhibiting osteoclast development Induced by the receptor for activation of nuclear factor kappa B ligand (RANKL), comprising the step of contacting said osteoclast, or a precursor of the osteoclast, with a pharmacologically effective dose of compounds such as diferuloylmethane, guggulsterone, 1'-Acetoxychavicol or analogues thereof.

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Inventors:

AGGARWAL BHARAT (US)

Application Number:

PCT/US2004/027639

Publication Date:

August 03, 2006

Filing Date:

August 25, 2004

Export Citation:

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Assignee:

RES DEV FOUNDATION (US)
AGGARWAL BHARAT (US)

International Classes:

A61K31/12; A61K31/56; A61P19/08; A61P19/10

Foreign References:

US20030118672A1	2003-06-26
US5494668A	1996-02-27
US6492333B1	2002-12-10

Other References: