Title:
PEPTIDE LIBRARY PRODUCTION METHOD
Document Type and Number:
WIPO Patent Application WO/2020/080490
Kind Code:
A1
Abstract:
The present invention provides a peptide library production method comprising a step for bringing a peptide library that includes peptides having amino acid sequences including at least one Trp or a derivative thereof, into contact with a prenylation enzyme, to prenylate at least a portion of amino acid residues included in at least a portion of the peptides.
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Inventors:
SUGA HIROAKI (JP)
GOTO YUKI (JP)
ABE IKURO (JP)
OKADA MASAHIRO (JP)
INOUE SUMIKA (JP)
GOTO YUKI (JP)
ABE IKURO (JP)
OKADA MASAHIRO (JP)
INOUE SUMIKA (JP)
Application Number:
PCT/JP2019/040975
Publication Date:
April 23, 2020
Filing Date:
October 17, 2019
Export Citation:
Assignee:
UNIV TOKYO (JP)
International Classes:
C40B40/10; C12P21/00; G01N33/53; C12N9/10; C12N15/11; C40B40/08
Domestic Patent References:
| WO2014181888A1 | 2014-11-13 | |||
| WO2014181888A1 | 2014-11-13 | |||
| WO2015030014A1 | 2015-03-05 |
Other References:
PARAJULI, ANIRUDRA: "A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 55, no. 11, 2016, pages 3596 - 3599, XP055703783, DOI: 10.1002/anie.201509920
H. MURAKAMIH. SAITOH. SUGA, CHEMISTRY &BIOLOGY, vol. 10, 2003, pages 655 - 662
BEILSTEIN, J ORG CHEM., vol. 13, 22 February 2017 (2017-02-22), pages 338 - 346
H. F. KUNG ET AL., THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 252, no. 19, 1977, pages 6889 - 6894
PROCEEDING OF NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 82, 1985, pages 1648 - 1652
M. Y. PAVLOVM. EHRENBERG, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 328, no. 1, 1996, pages 9 - 16
Y. SHIMIZU ET AL., NATURE BIOTECHNOLOGY, vol. 19, no. 8, 2001, pages 751 - 755
H. OHASHI ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 352, no. 1, 2007, pages 270 - 276
KAWAKAMI, T. ET AL., NATURE CHEMICAL BIOLOGY, vol. 5, 2009, pages 888 - 890
YAMAGISHI, Y. ET AL., CHEMBIOCHEM, vol. 10, 2009, pages 1469 - 1472
SAKO, Y. ET AL., JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 130, 2008, pages 7932 - 7934
GOTO, Y. ET AL., ACS CHEMICAL BIOLOGY, vol. 3, 2008, pages 120 - 129
KAWAKAMI T. ET AL., CHEMISTRY & BIOLOGY, vol. 15, 2008, pages 32 - 42
TETRAHEDRON, vol. 52, 1996, pages 9025
YAMAGISHI, Y. ET AL., CHEMISTRY & BIOLOGY, vol. 18, no. 12, 2011, pages 1562 - 70
H. MURAKAMIH. SAITOH. SUGA, CHEMISTRY &BIOLOGY, vol. 10, 2003, pages 655 - 662
BEILSTEIN, J ORG CHEM., vol. 13, 22 February 2017 (2017-02-22), pages 338 - 346
H. F. KUNG ET AL., THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 252, no. 19, 1977, pages 6889 - 6894
PROCEEDING OF NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 82, 1985, pages 1648 - 1652
M. Y. PAVLOVM. EHRENBERG, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 328, no. 1, 1996, pages 9 - 16
Y. SHIMIZU ET AL., NATURE BIOTECHNOLOGY, vol. 19, no. 8, 2001, pages 751 - 755
H. OHASHI ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 352, no. 1, 2007, pages 270 - 276
KAWAKAMI, T. ET AL., NATURE CHEMICAL BIOLOGY, vol. 5, 2009, pages 888 - 890
YAMAGISHI, Y. ET AL., CHEMBIOCHEM, vol. 10, 2009, pages 1469 - 1472
SAKO, Y. ET AL., JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 130, 2008, pages 7932 - 7934
GOTO, Y. ET AL., ACS CHEMICAL BIOLOGY, vol. 3, 2008, pages 120 - 129
KAWAKAMI T. ET AL., CHEMISTRY & BIOLOGY, vol. 15, 2008, pages 32 - 42
TETRAHEDRON, vol. 52, 1996, pages 9025
YAMAGISHI, Y. ET AL., CHEMISTRY & BIOLOGY, vol. 18, no. 12, 2011, pages 1562 - 70
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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