Title:
PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION WITH A STATIN
Document Type and Number:
WIPO Patent Application WO/2013/034436
Kind Code:
A1
Abstract:
The invention relates to a pharmaceutical composition for oral administration comprising or consisting of (i) 10 to 30 % weight,
of at least one pharmaceutically active substance selected from the group consisting of water-soluble, oxidatively-degradable statins,
preferably atorvastatin, cerivastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin or a combination thereof,(ii) 0.01 to 3 % weight, of a first anti-oxidatively active substance (A1), (iii) 0.01 to 3 % weight, of a second anti-oxidatively active substance (A2) that differs from the first anti-oxidatively active substance (A1), and (iv) 60 to 85 % weight of at least one additive, selected from the group consisting of filler, binder, flow- regulating agent, disintegrant and anti-blocking agent or a combination thereof, and the use of the pharmaceutical composition in medicine.
Inventors:
TAEUBRICH THERESA (DE)
ROTHER PATRICK (DE)
ROTHER PATRICK (DE)
Application Number:
PCT/EP2012/066288
Publication Date:
March 14, 2013
Filing Date:
August 21, 2012
Export Citation:
Assignee:
HEXAL AG (DE)
TAEUBRICH THERESA (DE)
ROTHER PATRICK (DE)
TAEUBRICH THERESA (DE)
ROTHER PATRICK (DE)
International Classes:
A61K9/20; A61K47/10; A61K47/12
Domestic Patent References:
| WO2004010933A2 | 2004-02-05 |
Foreign References:
| EP1992343A1 | 2008-11-19 | |||
| KR20050030282A | 2005-03-30 | |||
| KR20050030282A | 2005-03-30 |
Attorney, Agent or Firm:
BAUMANN, Rüdiger (DE)
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Claims: