PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE

Title:

PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE

Document Type and Number:

WIPO Patent Application WO2005115330

Kind Code:

A3

Abstract:

Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and hydroxypropyl methyl cellulose acetate (HPMCA) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility drug and such polymers, the polymers provide enhanced aqueous concentrations and/or improved physical stability.

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Inventors:

BABCOCK WALTER CHRISTIAN (US)
FRIESEN DWAYNE THOMAS (US)
LYON DAVID KEITH (US)
MILLER WARREN KENYON (US)
SMITHEY DANIEL TOD (US)

Application Number:

PCT/IB2005/001580

Publication Date:

July 06, 2006

Filing Date:

May 18, 2005

Export Citation:

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Assignee:

PFIZER PROD INC (US)
BABCOCK WALTER CHRISTIAN (US)
FRIESEN DWAYNE THOMAS (US)
LYON DAVID KEITH (US)
MILLER WARREN KENYON (US)
SMITHEY DANIEL TOD (US)

International Classes:

A61K9/16; A61K9/00; A61K9/14; C08B13/00

Foreign References:

US4226981A	1980-10-07
US6548555B1	2003-04-15
EP0580860A1	1994-02-02
EP0344603A1	1989-12-06
US20030054038A1	2003-03-20
US20030185891A1	2003-10-02
US20030219489A1	2003-11-27

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