Title:
PHARMACEUTICAL PRODUCT AND METHODS AND APPARATUS FOR MAKING SAME
Document Type and Number:
WIPO Patent Application WO1999063972
Kind Code:
A9
Abstract:
The present invention provides a product (1) that includes a pharmaceutical unit dosage or diagnostic form (6) that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount. In one embodiment, the unit form comprises a substrate (8), a deposit (14) that is disposed on the substrate and a cover layer (9) that overlies the deposit and is joined to the substrate by a bond that encircles that deposit, thereby encapsulating it between the substrate and cover substrates. The deposit comprises a powder, at least some of which includes the at least one active ingredient. The unit form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.
Inventors:
CHEN JEN-CHI (US)
CHRAI SUGGY S (US)
DESAI NITIN VITHALBHAI (US)
HAMMER LAWRENCE HARRISON (US)
KELLER DAVID (US)
KUMAR NALIN (US)
LAL PRINCE (US)
LEVINE AARON WILLIAM (US)
MURARI RAMASWAMY (US)
O'MARA KERRY DENNIS (US)
POLINIAK EUGENE SAMUEL (US)
RIVENBURG HOWARD CHRISTOPHER (US)
ROACH WILLIAM RONALD (US)
ROSATI DOMINIC STEPHEN (US)
SINGH BAWA (US)
SOUTHGATE PETER DAVID (US)
SUN HOI CHEONG (US)
ZANZUCCHI PETER JOHN (US)
CHRAI SUGGY S (US)
DESAI NITIN VITHALBHAI (US)
HAMMER LAWRENCE HARRISON (US)
KELLER DAVID (US)
KUMAR NALIN (US)
LAL PRINCE (US)
LEVINE AARON WILLIAM (US)
MURARI RAMASWAMY (US)
O'MARA KERRY DENNIS (US)
POLINIAK EUGENE SAMUEL (US)
RIVENBURG HOWARD CHRISTOPHER (US)
ROACH WILLIAM RONALD (US)
ROSATI DOMINIC STEPHEN (US)
SINGH BAWA (US)
SOUTHGATE PETER DAVID (US)
SUN HOI CHEONG (US)
ZANZUCCHI PETER JOHN (US)
Application Number:
PCT/US1999/012772
Publication Date:
October 12, 2000
Filing Date:
June 08, 1999
Export Citation:
Assignee:
DELSYS PHARMACEUTICAL CORP (US)
CHEN JEN CHI (US)
CHRAI SUGGY S (US)
DESAI NITIN VITHALBHAI (US)
HAMMER LAWRENCE HARRISON (US)
KELLER DAVID (US)
KUMAR NALIN (US)
LAL PRINCE (US)
LEVINE AARON WILLIAM (US)
MURARI RAMASWAMY (US)
MARA KERRY DENNIS O (US)
POLINIAK EUGENE SAMUEL (US)
RIVENBURG HOWARD CHRISTOPHER (US)
ROACH WILLIAM RONALD (US)
ROSATI DOMINIC STEPHEN (US)
SINGH BAWA (US)
SOUTHGATE PETER DAVID (US)
SUN HOI CHEONG (US)
ZANZUCCHI PETER JOHN (US)
CHEN JEN CHI (US)
CHRAI SUGGY S (US)
DESAI NITIN VITHALBHAI (US)
HAMMER LAWRENCE HARRISON (US)
KELLER DAVID (US)
KUMAR NALIN (US)
LAL PRINCE (US)
LEVINE AARON WILLIAM (US)
MURARI RAMASWAMY (US)
MARA KERRY DENNIS O (US)
POLINIAK EUGENE SAMUEL (US)
RIVENBURG HOWARD CHRISTOPHER (US)
ROACH WILLIAM RONALD (US)
ROSATI DOMINIC STEPHEN (US)
SINGH BAWA (US)
SOUTHGATE PETER DAVID (US)
SUN HOI CHEONG (US)
ZANZUCCHI PETER JOHN (US)
International Classes:
A61K9/14; A61J3/00; A61K9/16; A61K9/51; A61K9/70; B05B5/025; B05B5/16; B65B1/04; B65B1/30; B65B11/50; A61J1/03; B05B5/08; (IPC1-7): A61K9/70
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