Title:
PIPERIDINE-1-CARBOXAMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2005/090340
Kind Code:
A1
Abstract:
Disclosed is a compound represented by the following general formula (I): (I) [wherein Ar1 represents an optionally substituted aryl group or heteroaryl group; R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 independently represent a hydrogen atom, a hydroxyl group, a lower alkyl group, an aralkyl group or an aryl group; T, U, V and W independently represent an optionally substituted methine group or a nitrogen atom and at least one of them represents a methine group; X represents a single bond, a methylene group or an ethylene group; and Y represents a single bond or a group expressed as -O-, -C(R1)(R2)-, -O-C(R3)(R4)-, -C(R5)(R6)-O- or -C(R7)(R8)-C(R9)(R10)-]. This compound is useful as an agent for the treatment of various diseases associated with NPY.
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Inventors:
TAKAHASHI TOSHIYUKI (JP)
KANATANI AKIO (JP)
KANATANI AKIO (JP)
Application Number:
PCT/JP2005/004871
Publication Date:
September 29, 2005
Filing Date:
March 14, 2005
Export Citation:
Assignee:
BANYU PHARMA CO LTD (JP)
TAKAHASHI TOSHIYUKI (JP)
KANATANI AKIO (JP)
TAKAHASHI TOSHIYUKI (JP)
KANATANI AKIO (JP)
International Classes:
A61K31/415; A61K31/454; A61K31/4709; A61K31/497; A61P1/00; A61P1/04; A61P1/14; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P3/12; A61P5/00; A61P5/28; A61P5/50; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P11/08; A61P13/10; A61P13/12; A61P15/06; A61P15/08; A61P15/10; A61P17/00; A61P19/02; A61P19/06; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/06; A61P29/00; C07D231/14; C07D413/04; C07D413/14; C07D417/14; (IPC1-7): C07D413/14; A61K31/415; A61K31/454; A61K31/4709; A61K31/497; A61P1/00; A61P1/04; A61P1/14; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P3/12; A61P5/00; A61P5/28; A61P5/50; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P11/08; A61P13/10; A61P13/12; A61P15/06; A61P15/08; A61P15/10; A61P17/00; A61P19/02; A61P19/06; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/06; A61P29/00; C07D231/14; C07D413/04; C07D417/14
Domestic Patent References:
| WO2003084952A1 | 2003-10-16 | |||
| WO2003037332A1 | 2003-05-08 | |||
| WO2002051806A1 | 2002-07-04 | |||
| WO2004011440A1 | 2004-02-05 | |||
| WO2003045313A2 | 2003-06-05 |
Foreign References:
| JP2001519812A | 2001-10-23 | |||
| JPH0887747A | 1996-04-02 |
Other References:
TORRENS A. ET AL.: "Synthesis of new benzoxazione derivatives as neuropeptide Y5 antagonist for the treatment of obesity.", J. MED.CHEM., vol. 48, 2005, pages 2080 - 2092, XP002986119
Attorney, Agent or Firm:
BANYU PHARMACEUTICAL CO., LTD. (1-13-12 Kudankit, Chiyoda-ku Tokyo 67, JP)
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