Title:
PROBIOTIC MOMORDICA CHARANTIA FERMENTATE WITH ENHANCED ANTI-DIABETIC, ANTI-DEMENTIA, AND ANTI-OXIDATIVE FUNCTION
Document Type and Number:
WIPO Patent Application WO/2023/282577
Kind Code:
A1
Abstract:
The present invention relates to a probiotic Momordica charantia fermentate with enhanced anti-diabetic, anti-dementia, and anti-oxidative functions and a preparation method therefor and, more specifically, provides a method for preparing a Momordica charantia fermentate having enhanced anti-dementia activity and a Momordica charantia fermentate prepared according thereto, wherein the method comprises the steps of: adding a sugar ingredient to prepare a Momordica charantia fermentate with a sugar content of 3 to 15 degrees Brix; and fermenting the prepared mixture by inoculating a probiotic strain thereinto. With enhanced anti-dementia, anti-diabetic, and anti-oxidative activities, the Momordica charantia fermentate can be applied to a pharmaceutical composition and a health functional food composition for prevention, treatment, or alleviation of cognitive impairment or diabetes mellitus.
Inventors:
KIM MISOOK (KR)
JEONG YOONHWA (KR)
RYU JAESIK (KR)
SEONG HUI-YEONG (KR)
OH SU JIN (KR)
YOON JIWON (KR)
JANG HYUNAH (KR)
CHOI JIN A (KR)
JEONG YOONHWA (KR)
RYU JAESIK (KR)
SEONG HUI-YEONG (KR)
OH SU JIN (KR)
YOON JIWON (KR)
JANG HYUNAH (KR)
CHOI JIN A (KR)
Application Number:
PCT/KR2022/009657
Publication Date:
January 12, 2023
Filing Date:
July 05, 2022
Export Citation:
Assignee:
UNIV DANKOOK CHEONAN CAMPUS IND ACADEMIC COOPERATION FOUNDATION (KR)
International Classes:
A61K36/42; A23L29/00; A23L33/105; A61P3/10; A61P25/28; A61P39/06
Domestic Patent References:
| WO2019209086A1 | 2019-10-31 |
Foreign References:
| KR20180116052A | 2018-10-24 | |||
| KR102191775B1 | 2020-12-16 | |||
| JP2021019506A | 2021-02-18 | |||
| KR20160049732A | 2016-05-10 |
Other References:
KIM KKOT BYEOL, LEE SEONAH, HEO JAE HYEOK, KIM JUNG HEE: "Neuroprotective effects of Momordica charantia extract against hydrogen peroxide-induced cytotoxicity in human neuroblastoma SK-N-MC cells", THE KOREAN JOURNAL OF NUTRITION, vol. 50, no. 5, 1 January 2017 (2017-01-01), pages 415 - 425, XP093020522, ISSN: 2288-3886, DOI: 10.4163/jnh.2017.50.5.415
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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