Title:
PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE PREPARATION OF COMPOUNDS THAT MODULATE SPLICING
Document Type and Number:
WIPO Patent Application WO/2022/032007
Kind Code:
A3
Abstract:
Described herein are processes for preparing compounds useful in the preparation of small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and compounds used in such processes.
Inventors:
LUZZIO MICHAEL (US)
WANG TIANSHENG (US)
WANG TIANSHENG (US)
Application Number:
PCT/US2021/044804
Publication Date:
March 10, 2022
Filing Date:
August 05, 2021
Export Citation:
Assignee:
SKYHAWK THERAPEUTICS INC (US)
International Classes:
A61K31/454; A61K31/517; C12Q1/37
Domestic Patent References:
| WO2019028440A1 | 2019-02-07 | |||
| WO2019191229A1 | 2019-10-03 |
Foreign References:
| US20160280721A1 | 2016-09-29 |
Other References:
DATABASE PubChem 2 June 2019 (2019-06-02), XP055915456, Database accession no. 151978989
ONO ET AL.: "Regioselective Preparation of Allylic Sulfones by Palladium-Catalyzed Reactions of Allylic Nitro Compounds with Sodium Benzenesulfinate", BULL. CHEM. SOC. JPN., vol. 59, 1986, pages 405 - 410, XP055915474
ONO ET AL.: "Regioselective Preparation of Allylic Sulfones by Palladium-Catalyzed Reactions of Allylic Nitro Compounds with Sodium Benzenesulfinate", BULL. CHEM. SOC. JPN., vol. 59, 1986, pages 405 - 410, XP055915474
Attorney, Agent or Firm:
KUZNETSOV, Alexey, G. (US)
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