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Title:
PROCESS FOR PREPARING OPTICALLY ACTIVE PHENYLOXIRANE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO1998056762
Kind Code:
A3
Abstract:
A process for preparing an optically active phenyloxirane compound represented by formula (II), wherein ring A is a substitued or unsubstituted benzene ring; R is a group represented by -CO2R, or a group convertible to the group represented by -CO2R, wherein R is an ester residue; and * indicates an asymmetric carbon atom, comprising treating a styrene derivative (I) represented by the formula (I), wherein ring A and R are the same as defined above, with an asymmetric oxidation agent formed from a chiral ketone compound and an oxidizing agent, or a chiral dioxirane compound.

Inventors:
HASHIYAMA TOMIKI (JP)
HARADA NAOYUKI (JP)
ARAKAWA HIROAKI (JP)
KUSAMA MARI (JP)
OZAKI YASUHIKO (JP)
KURODA TOORU (JP)
SEKI MASAHIKO (JP)
Application Number:
PCT/JP1998/002521
Publication Date:
March 25, 1999
Filing Date:
June 05, 1998
Export Citation:
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Assignee:
TANABE SEIYAKU CO (JP)
HASHIYAMA TOMIKI (JP)
HARADA NAOYUKI (JP)
ARAKAWA HIROAKI (JP)
KUSAMA MARI (JP)
OZAKI YASUHIKO (JP)
KURODA TOORU (JP)
SEKI MASAHIKO (JP)
International Classes:
C07C319/14; C07D281/10; C07D301/16; C07D303/16; C07C323/56; (IPC1-7): C07D301/03; C07D281/10; C07C323/62
Foreign References:
GB2139620A1984-11-14
FR2662178A11991-11-22
EP0498706A11992-08-12
EP0342903A11989-11-23
EP0362556A11990-04-11
EP0343714A11989-11-29
Other References:
DAN YANG ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 118, 1996, pages 11311 - 2, XP002076047
R. W. MURRAY, CHEMICAL REVIEWS, vol. 89, 1989, pages 1187 - 1201, XP002076048
A. ARMSTRONG ET AL., CHEMICAL COMMUNICATIONS, no. 5, 1998, pages 621 - 2, XP002076049
PATENT ABSTRACTS OF JAPAN vol. 18, no. 334 (C - 1216) 24 June 1994 (1994-06-24)
S. MIYANO ET AL., BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 57, 1984, pages 1943 - 7, XP002076050
PATENT ABSTRACTS OF JAPAN vol. 95, no. 1 28 February 1995 (1995-02-28)
PATENT ABSTRACTS OF JAPAN vol. 9, no. 125 (C - 283) 30 May 1985 (1985-05-30)
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