Title:
REMEDIES FOR ARTHRITIS DEFORMANS
Document Type and Number:
WIPO Patent Application WO/2003/080041
Kind Code:
A1
Abstract:
It is intended to provide remedies or preventives for arthritis deformans and/or rheumatoid arthritis comprising as the active ingredient a compound represented by the following formula (I), its optical isomers, prodrugs thereof or pharmaceutically acceptable salts thereof, or solvates of the same.
Inventors:
GEMBA TAKEFUMI (JP)
WATANABE FUMIHIKO (JP)
WATANABE FUMIHIKO (JP)
Application Number:
PCT/JP2003/003672
Publication Date:
October 02, 2003
Filing Date:
March 26, 2003
Export Citation:
Assignee:
SHIONOGI & CO (JP)
GEMBA TAKEFUMI (JP)
WATANABE FUMIHIKO (JP)
GEMBA TAKEFUMI (JP)
WATANABE FUMIHIKO (JP)
International Classes:
A61P19/02; A61P29/00; C07C311/29; C07C323/67; C07D271/06; C07D277/26; C07D333/34; (IPC1-7): A61K31/198; A61K31/381; A61K31/4245; A61K31/426; A61P19/02; A61P29/00
Domestic Patent References:
| WO2001083464A1 | 2001-11-08 | |||
| WO2002028844A1 | 2002-04-11 |
Foreign References:
| JPH11246527A | 1999-09-14 | |||
| JP2001335575A | 2001-12-04 | |||
| JP2001261656A | 2001-09-26 | |||
| JP2000143650A | 2000-05-26 |
Other References:
TAMURA YOSHINORI ET AL.: "Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives", JOURNAL OF MEDICINAL CHEMISTRY, vol. 41, no. 4, 1998, pages 640 - 649, XP002072052
Attorney, Agent or Firm:
Yamauchi, Hideaki (Intellectual Property Department, 12-4, Sagisu
5-chome, Fukushima-k, Osaka-shi Osaka, JP)
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