Title:
RETINOID FORMULATIONS FOR AEROSOLIZATION AND INHALATION
Document Type and Number:
WIPO Patent Application WO2001066104
Kind Code:
A3
Abstract:
Formulations and methods for prevention and treatment of preneoplasia or neoplasia of the aerodigestive tract and lungs by means of inhaled aerosol of retinoids, and 13-cis RA in particular.
More Like This:
| WO/2020/193779 | MULTICOMPONENT THERMOPLASTIC PRODUCT |
| WO2006083979 | LOCAL TREATMENT OF NEUROFIBROMAS |
| WO/1991/016929 | A PHARMACEUTICAL PREPARATION CONTAINING N-GLYCOFUROLS AND N-ETHYLENE GLYCOLS |
Inventors:
DAHL ALAN R (US)
PLACKE MICHAEL E (US)
ZIMLICH WILLIAM C JR (US)
DE LUCA LUIGI M (US)
MULSHINE JAMES L (US)
PLACKE MICHAEL E (US)
ZIMLICH WILLIAM C JR (US)
DE LUCA LUIGI M (US)
MULSHINE JAMES L (US)
Application Number:
PCT/US2001/007123
Publication Date:
January 24, 2002
Filing Date:
March 07, 2001
Export Citation:
Assignee:
BATTELLE MEMORIAL INSTITUTE (US)
DAHL ALAN R (US)
PLACKE MICHAEL E (US)
ZIMLICH WILLIAM C JR (US)
LUCA LUIGI M DE (US)
MULSHINE JAMES L (US)
DAHL ALAN R (US)
PLACKE MICHAEL E (US)
ZIMLICH WILLIAM C JR (US)
LUCA LUIGI M DE (US)
MULSHINE JAMES L (US)
International Classes:
A61K9/00; A61K31/07; (IPC1-7): A61K31/07; A61K9/72; A61P35/00
Domestic Patent References:
| WO1997039745A1 | 1997-10-30 | |||
| WO2001010252A1 | 2001-02-15 |
Foreign References:
| US5112598A | 1992-05-12 | |||
| EP0003064A2 | 1979-07-25 |
Other References:
MULSHINE, JAMES L. ET AL: "Regional delivery of retinoids: a new approach to early lung cancer intervention", CLIN. BIOL. BASIS LUNG CANCER PREV. (1998), 273-283. EDITOR(S): MARTINET, YVES. PUBLISHER: BIRKHAEUSER, BASEL, SWITZ., XP001017973
MULSHINE J.L.: "Reducing lung cancer risk: Early detection.", CHEST, (1999) 116/6 SUPPL. (493S-496S)., XP001018002
RALEIGH S M ET AL: "Pharmacokinetics of isotretinoin (ISO) in rats following oral dosing or aerosol inhalation.", BRITISH JOURNAL OF CANCER, vol. 80, no. SUPPL. 2, July 1999 (1999-07-01), Joint Meeting of the British Association for Cancer Research, the British Oncological Association, the Association of Cancer Physicians and the Royal College of Radiologists;Edinburgh, Scotland, UK; J, pages 96, XP001012842, ISSN: 0007-0920
RALEIGH S M ET AL: "Preclinical evaluation of an isotretinoin (iso) powder formulation for aerosol administration in lung cancer chemoprevention.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL, vol. 40, March 1999 (1999-03-01), 90th Annual Meeting of the American Association for Cancer Research;Philadelphia, Pennsylvania, USA; April 10-14, 1999, March, 1999, pages 397, XP001019061, ISSN: 0197-016X
MULSHINE J.L.: "Reducing lung cancer risk: Early detection.", CHEST, (1999) 116/6 SUPPL. (493S-496S)., XP001018002
RALEIGH S M ET AL: "Pharmacokinetics of isotretinoin (ISO) in rats following oral dosing or aerosol inhalation.", BRITISH JOURNAL OF CANCER, vol. 80, no. SUPPL. 2, July 1999 (1999-07-01), Joint Meeting of the British Association for Cancer Research, the British Oncological Association, the Association of Cancer Physicians and the Royal College of Radiologists;Edinburgh, Scotland, UK; J, pages 96, XP001012842, ISSN: 0007-0920
RALEIGH S M ET AL: "Preclinical evaluation of an isotretinoin (iso) powder formulation for aerosol administration in lung cancer chemoprevention.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL, vol. 40, March 1999 (1999-03-01), 90th Annual Meeting of the American Association for Cancer Research;Philadelphia, Pennsylvania, USA; April 10-14, 1999, March, 1999, pages 397, XP001019061, ISSN: 0197-016X
Download PDF:
Previous Patent: TREATMENT OF NEOPLASMS BY INHALATION OF CARBOPLATIN
Next Patent: METHOD AND COMPOSITION FOR LIGHTENING THE SKIN
Next Patent: METHOD AND COMPOSITION FOR LIGHTENING THE SKIN