Title:
SARS-CORONAVIRUS INFECTION DIAGNOSIS BINDING MOLECULE THAT BINDS TO SPIKE PROTEIN ON SURFACE OF SARS-CORONAVIRUS-2
Document Type and Number:
WIPO Patent Application WO/2022/050709
Kind Code:
A1
Abstract:
The present invention relates to a SARS-coronavirus infection diagnosis binding molecule that binds to a spike protein on the surface of SARS-coronavirus-2. More specifically, a binding molecule of the present invention has excellent binding ability to an S protein of SARS-CoV-2 to exhibit excellent diagnosis effects, and thus is very useful in the rapid diagnosis of a SARS-coronavirus infection (COVID-19).
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| WO/2021/233433 | ANTI-SARS-COV-2 SPIKE PROTEIN MONOCLONAL ANTIBODY |
| WO/2022/089044 | ANTIBODY AGAINST NOVEL CORONAVIRUS, REAGENT FOR DETECTING NOVEL CORONAVIRUS, AND TEST KIT |
| WO/2008/083432 | RECOMBINANT ANTIBODIES |
Inventors:
HUH PHILIPP (KR)
KIM MIN SOO (KR)
KIM CHEOL MIN (KR)
SEO JI MIN (KR)
LEE SOO YOUNG (KR)
KWON KI SUNG (KR)
KIM MIN SOO (KR)
KIM CHEOL MIN (KR)
SEO JI MIN (KR)
LEE SOO YOUNG (KR)
KWON KI SUNG (KR)
Application Number:
PCT/KR2021/011827
Publication Date:
March 10, 2022
Filing Date:
September 02, 2021
Export Citation:
Assignee:
CELLTRION INC (KR)
International Classes:
C07K16/10; C12N15/85; G01N33/569
Foreign References:
| KR20080012449A | 2008-02-12 | |||
| KR102229225B1 | 2021-03-19 |
Other References:
PARRAY HILAL AHMAD, CHIRANJIVI ADARSH KUMAR, ASTHANA SHAILENDRA, YADAV NAVEEN, SHRIVASTAVA TRIPTI, MANI SHAILENDRA, SHARMA CHANDRE: "Identification of an anti–SARS–CoV-2 receptor-binding domain–directed human monoclonal antibody from a naïve semisynthetic library", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 295, no. 36, 1 September 2020 (2020-09-01), US , pages 12814 - 12821, XP055899844, ISSN: 0021-9258, DOI: 10.1074/jbc.AC120.014918
BOORLA VEDA SHEERSH, CHOWDHURY RATUL, MARANAS COSTAS D.: "De novo design of high-affinity antibody variable regions (Fv) against the SARS-CoV-2 spike protein", BIORXIV, 11 April 2020 (2020-04-11), pages 1 - 13, XP055861231, DOI: 10.1101/2020.04.09.034868
DATABASE Protein 15 June 2020 (2020-06-15), "anti-SARS-CoV-2 monoclonal antibody light chain variable region, partial [Homo sapiens]", XP55910280, retrieved from NCBI Database accession no. QKQ15280
DATABASE Protein 22-07-2020, "anti-SARS-CoV-2 immunoglobulin heavy chain variable region, partial [Homo sapiens]", XP055910265, retrieved from NCBI Database accession no. QLI62509
BOORLA VEDA SHEERSH, CHOWDHURY RATUL, MARANAS COSTAS D.: "De novo design of high-affinity antibody variable regions (Fv) against the SARS-CoV-2 spike protein", BIORXIV, 11 April 2020 (2020-04-11), pages 1 - 13, XP055861231, DOI: 10.1101/2020.04.09.034868
DATABASE Protein 15 June 2020 (2020-06-15), "anti-SARS-CoV-2 monoclonal antibody light chain variable region, partial [Homo sapiens]", XP55910280, retrieved from NCBI Database accession no. QKQ15280
DATABASE Protein 22-07-2020, "anti-SARS-CoV-2 immunoglobulin heavy chain variable region, partial [Homo sapiens]", XP055910265, retrieved from NCBI Database accession no. QLI62509
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