SENSOR CHIP FOR USE IN MEASURING INTERMOLECULAR INTERACTIONS, HAVING BEEN SUBJECTED TO NONSPECIFIC-ADSORPTION INHIBITION TREATMENT USING SURFACTANT, PROCESS FOR PRODUCING SAID SENSOR CHIP, AND METHOD FOR MEASURING INTERMOLECULAR INTERACTIONS USING SAID SENSOR CHIP

WIPO Patent Application WO/2013/002193

A1

The present invention provides a means for measuring intermolecular interactions which uses an improved nonspecific-adsorption inhibitor that neither peels away even when brought into contact with a regenerating solution nor hinders an intermolecular interaction between a ligand and an analyte. This process for producing a sensor chip for use in measuring intermolecular interactions is characterized by including a nonspecific-adsorption inhibition treatment step of bringing an aqueous solution of a surfactant into contact with a measuring part where a ligand is immobilized on the surface of a layer consisting of SiN, Ta2O5, Nb2O5, HfO2, ZrO2 or ITO (indium tin oxide) and thereby forming a coating film of the surfactant on the measuring part. The surfactant is preferably a nonionic surfactant. It is preferable that the aqueous solution of a surfactant has a concentration of 0.0001 to 0.1wt%.

KURIHARA YOSHIKAZU (JP)

PCT/JP2012/066209

January 03, 2013

June 26, 2012

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KONICA MINOLTA ADVANCED LAYERS (JP)
KURIHARA YOSHIKAZU (JP)

G01N33/543; G01N21/27; G01N21/45; G01N37/00

JP2009142283A	2009-07-02
JP3786073B2	2006-06-14
JPH10307141A	1998-11-17

YOSHIKAZU KURIHARA ET AL.: "Intermolecular interaction measuring apparatus using reflectometric interference spectroscopy", KONICA MINOLTA TECHNOL REP, vol. 8, January 2011 (2011-01-01), pages 134 - 137

SSINPAT PATENT FIRM (JP)
Patent business corporation SSINPAT (JP)

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