Title:
SOFT TISSUE REPAIR AND REGENERATION USING POSTPARTUM-DERIVED CELLS
Document Type and Number:
WIPO Patent Application WO2005001079
Kind Code:
A3
Abstract:
Cells derived from postpartum tissue having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.
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Inventors:
HARMON ALEXANDER M (US)
HARRIS IAN ROSS (US)
KIHM ANTHONY J (US)
MISTRY SANJAY (US)
MESSINA DARIN J (US)
SEYDA AGNIESZKA (US)
YI CHIN-FENG (US)
GOSIEWSKA ANNA (US)
HARRIS IAN ROSS (US)
KIHM ANTHONY J (US)
MISTRY SANJAY (US)
MESSINA DARIN J (US)
SEYDA AGNIESZKA (US)
YI CHIN-FENG (US)
GOSIEWSKA ANNA (US)
Application Number:
PCT/US2004/020956
Publication Date:
April 28, 2005
Filing Date:
June 25, 2004
Export Citation:
Assignee:
ETHICON INC (US)
HARMON ALEXANDER M (US)
HARRIS IAN ROSS (US)
KIHM ANTHONY J (US)
MISTRY SANJAY (US)
MESSINA DARIN J (US)
SEYDA AGNIESZKA (US)
YI CHIN-FENG (US)
GOSIEWSKA ANNA (US)
HARMON ALEXANDER M (US)
HARRIS IAN ROSS (US)
KIHM ANTHONY J (US)
MISTRY SANJAY (US)
MESSINA DARIN J (US)
SEYDA AGNIESZKA (US)
YI CHIN-FENG (US)
GOSIEWSKA ANNA (US)
International Classes:
C12N5/073; C12N5/074; (IPC1-7): C12N5/06
Domestic Patent References:
| WO2003068937A2 | 2003-08-21 |
Foreign References:
| US20030032179A1 | 2003-02-13 | |||
| US5919702A | 1999-07-06 | |||
| US20030161818A1 | 2003-08-28 |
Other References:
MITCHELL K E ET AL: "Matrix cells from Wharton's jelly form neurons and glia", STEM CELLS, ALPHAMED PRESS, DAYTON, OH, US, vol. 21, no. 1, January 2003 (2003-01-01), pages 50 - 60, XP002281007, ISSN: 1066-5099
RAFII SHAHIN ET AL: "Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration.", NATURE MEDICINE, vol. 9, no. 6, June 2003 (2003-06-01), pages 702 - 712, XP002312846, ISSN: 1078-8956
RABBANY SINA Y ET AL: "Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization.", TRENDS IN MOLECULAR MEDICINE, vol. 9, no. 3, March 2003 (2003-03-01), pages 109 - 117, XP002312847, ISSN: 1471-4914
JACKSON K A ET AL: "Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells", JOURNAL OF CLINICAL INVESTIGATION, NEW YORK, NY, US, vol. 107, no. 11, June 2001 (2001-06-01), pages 1395 - 1402, XP002976368, ISSN: 0021-9738
RAFII SHAHIN ET AL: "Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration.", NATURE MEDICINE, vol. 9, no. 6, June 2003 (2003-06-01), pages 702 - 712, XP002312846, ISSN: 1078-8956
RABBANY SINA Y ET AL: "Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization.", TRENDS IN MOLECULAR MEDICINE, vol. 9, no. 3, March 2003 (2003-03-01), pages 109 - 117, XP002312847, ISSN: 1471-4914
JACKSON K A ET AL: "Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells", JOURNAL OF CLINICAL INVESTIGATION, NEW YORK, NY, US, vol. 107, no. 11, June 2001 (2001-06-01), pages 1395 - 1402, XP002976368, ISSN: 0021-9738
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