Title:
ST2 ANTIGEN BINDING PROTEINS
Document Type and Number:
WIPO Patent Application WO/2013/173761
Kind Code:
A3
Abstract:
Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and derivatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.
Inventors:
SMITH DIRK E (US)
FOLTZ IAN (CA)
KING CHADWICK T (CA)
LIM AI CHING (US)
CLARK RUTILIO (US)
COMEAU MICHAEL R (US)
KETCHEM RANDAL R (US)
SHI DONGHUI (US)
MIN XIAOSHAN (US)
WANG ZHULUN (US)
FOLTZ IAN (CA)
KING CHADWICK T (CA)
LIM AI CHING (US)
CLARK RUTILIO (US)
COMEAU MICHAEL R (US)
KETCHEM RANDAL R (US)
SHI DONGHUI (US)
MIN XIAOSHAN (US)
WANG ZHULUN (US)
Application Number:
PCT/US2013/041656
Publication Date:
February 20, 2014
Filing Date:
May 17, 2013
Export Citation:
Assignee:
AMGEN INC (US)
International Classes:
C07K16/28
Foreign References:
| US20100221257A1 | 2010-09-02 | |||
| US20100247545A1 | 2010-09-30 | |||
| US20100247442A1 | 2010-09-30 | |||
| US20090214559A1 | 2009-08-27 | |||
| US20110256635A1 | 2011-10-20 | |||
| US20050058639A1 | 2005-03-17 |
Other References:
See also references of EP 2850103A4
Attorney, Agent or Firm:
WRONA, Thomas J. (1201 Amgen Court W.Seattle, Washington, US)
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