Title:
SYSTEMS AND METHODS FOR MAKING NON-INVASIVE PHYSIOLOGICAL ASSESSMENTS
Document Type and Number:
WIPO Patent Application WO2002043564
Kind Code:
A9
Abstract:
Systems and methods for assessment of tissue properties, noninvasively, by acquiring data relating to at least one aspect of intrinsic and/or induced tissue displacement, or associated biological responses, are provided. Data relating to tissue displacement and associated biological changes may be acquired by detecting acoustic properties of tissue using ultrasound interrogation pulses, preferably in a scatter or Doppler detection mode. Based on this data, tissue properties are assessed, characterized and monitored. Specific applications for systems and methods of the present invention include non-invasive assessment and monitoring of intracranial pressure (ICP), arterial blood pressure (ABP), CNS autoregulation status, vasospasm, stroke, local edema, infection and vasculitus, as well as diagnosis and monitoring of diseases and conditions that are characterized by physical changes in tissue properties. Methods and systems for localizing physiological condition(s) and/or biological response(s), such as pain, by targeting and selectively palpating tissues using the application of acoustic radiation forces are also provided.
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Inventors:
MOURAD PIERRE
KLIOT MICHEL
MESIWALA ALI
PATTERSON REX
JARVIK JEFFREY G
KLIOT MICHEL
MESIWALA ALI
PATTERSON REX
JARVIK JEFFREY G
Application Number:
PCT/US2001/044433
Publication Date:
August 07, 2003
Filing Date:
November 28, 2001
Export Citation:
Assignee:
ALLEZ PHYSIONIX LTD (CA)
UNIV WASHINGTON (US)
UNIV WASHINGTON (US)
International Classes:
A61B8/08; A61B8/00; A61B5/03; A61B8/04; (IPC1-7): A61B8/00
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