Title:
TARGET-TISSUE-SPECIFIC ANTIGEN-BINDING MOLECULE
Document Type and Number:
WIPO Patent Application WO/2013/180200
Kind Code:
A1
Abstract:
The inventors of the present invention have invented an antigen-binding molecule, which contains an antigen-binding domain in which binding activity with respect to antigens changes depending on the concentration of a target-tissue-specific compound. Using the present antigen-binding molecule enables various diseases stemming from target tissues to be treated in a target-tissue-specific manner.
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Inventors:
IGAWA TOMOYUKI (JP)
TAMBA SHIGERO (JP)
TATSUMI KANAKO (JP)
SHIMIZU SHUN (JP)
KADONO SHOJIRO (JP)
TAMBA SHIGERO (JP)
TATSUMI KANAKO (JP)
SHIMIZU SHUN (JP)
KADONO SHOJIRO (JP)
Application Number:
PCT/JP2013/064975
Publication Date:
December 05, 2013
Filing Date:
May 30, 2013
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
International Classes:
C07K16/32; A61K39/395; A61P29/00; A61P35/00; C07K16/28; C07K16/46; G01N33/15; G01N33/50; G01N33/531; C12N15/09
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Masao Haruna (JP)
Masao Haruna (JP)
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