Title:
TOOTH-WHITENING GEL COMPRISING MODIFIED NIOBIUM COMPOUNDS, METHOD AND USE
Document Type and Number:
WIPO Patent Application WO/2022/023847
Kind Code:
A9
Abstract:
The present invention relates to a product for tooth whitening based on the generation of active oxygen in the form of radical oxygen species in situ. The whitening gel comprises modified niobium compounds and its activity is maximized primarily if it is applied with hydrogen peroxide in low concentrations of between 1 and 10% (preferably 3% by weight), with stabilization by a thickener, preferably carbopol. The whitening gel can be used for tooth whitening without any need for light in addition to the treatment, which allows the use thereof for tooth whitening in a more efficient manner than commercially available products and with significant potential for reduced side effects (hypersensitivity and inflammation). The product developed is not cytotoxic and no significant inflammatory effect has been observed in the pulp tissue. The present invention also describes a method for producing the whitening gel.
Inventors:
HEITMANN RODRIGUES ANA PACHELI (BR)
ALVES DE OLIVEIRA LUIZ CARLOS (BR)
BELCHIOR JADSON CLAUDIO (BR)
MORGAN DOS SANTOS ALVES LUIS FERNANDO (BR)
MAUAD DE ABREU FERNANDO ANTONIO (BR)
ALVES DE OLIVEIRA LUIZ CARLOS (BR)
BELCHIOR JADSON CLAUDIO (BR)
MORGAN DOS SANTOS ALVES LUIS FERNANDO (BR)
MAUAD DE ABREU FERNANDO ANTONIO (BR)
Application Number:
PCT/IB2021/056144
Publication Date:
March 24, 2022
Filing Date:
July 08, 2021
Export Citation:
Assignee:
UNIV FEDERAL DE MINAS GERAIS UFMG (BR)
ODONTO TECH PESQUISA E INOVACAO LTDA (BR)
ODONTO TECH PESQUISA E INOVACAO LTDA (BR)
International Classes:
A61K6/00; A61K6/17
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